Interleukins in cancer: from biology to therapy

D Briukhovetska, J Dörr, S Endres, P Libby… - Nature Reviews …, 2021 - nature.com
Interleukins and associated cytokines serve as the means of communication for innate and
adaptive immune cells as well as non-immune cells and tissues. Thus, interleukins have a …

The evolution of commercial drug delivery technologies

AM Vargason, AC Anselmo, S Mitragotri - Nature biomedical …, 2021 - nature.com
Drug delivery technologies have enabled the development of many pharmaceutical
products that improve patient health by enhancing the delivery of a therapeutic to its target …

Tumor‐microenvironment‐responsive nanomedicine for enhanced cancer immunotherapy

S Peng, F Xiao, M Chen, H Gao - Advanced Science, 2022 - Wiley Online Library
The past decades have witnessed great progress in cancer immunotherapy, which has
profoundly revolutionized oncology, whereas low patient response rates and potential …

Multifunctional biomolecule nanostructures for cancer therapy

J Wang, Y Li, G Nie - Nature Reviews Materials, 2021 - nature.com
Biomolecule-based nanostructures are inherently multifunctional and harbour diverse
biological activities, which can be explored for cancer nanomedicine. The supramolecular …

Bioengineered nanogels for cancer immunotherapy

X Ma, SJ Li, Y Liu, T Zhang, P Xue, Y Kang… - Chemical Society …, 2022 - pubs.rsc.org
Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …

Precision cancer sono-immunotherapy using deep-tissue activatable semiconducting polymer immunomodulatory nanoparticles

J Li, Y Luo, Z Zeng, D Cui, J Huang, C Xu, L Li… - Nature …, 2022 - nature.com
Nanomedicine holds promise to enhance cancer immunotherapy; however, its potential to
elicit highly specific anti-tumor immunity without compromising immune tolerance has yet to …

Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy

C Zhang, Z Zeng, D Cui, S He, Y Jiang, J Li… - Nature …, 2021 - nature.com
Immunometabolic intervention has been applied to treat cancer via inhibition of certain
enzymes associated with intratumoral metabolism. However, small-molecule inhibitors and …

Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer

Y Jiang, J Huang, C Xu, K Pu - Nature communications, 2021 - nature.com
Nanomedicine in combination with immunotherapy offers opportunities to treat cancer in a
safe and effective manner; however, remote control of immune response with spatiotemporal …

The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Immune cell Membrane‐Coated biomimetic nanoparticles for targeted cancer therapy

F Oroojalian, M Beygi, B Baradaran, A Mokhtarzadeh… - Small, 2021 - Wiley Online Library
Nanotechnology has provided great opportunities for managing neoplastic conditions at
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …