Interleukins in cancer: from biology to therapy
Interleukins and associated cytokines serve as the means of communication for innate and
adaptive immune cells as well as non-immune cells and tissues. Thus, interleukins have a …
adaptive immune cells as well as non-immune cells and tissues. Thus, interleukins have a …
The evolution of commercial drug delivery technologies
AM Vargason, AC Anselmo, S Mitragotri - Nature biomedical …, 2021 - nature.com
Drug delivery technologies have enabled the development of many pharmaceutical
products that improve patient health by enhancing the delivery of a therapeutic to its target …
products that improve patient health by enhancing the delivery of a therapeutic to its target …
Tumor‐microenvironment‐responsive nanomedicine for enhanced cancer immunotherapy
The past decades have witnessed great progress in cancer immunotherapy, which has
profoundly revolutionized oncology, whereas low patient response rates and potential …
profoundly revolutionized oncology, whereas low patient response rates and potential …
Multifunctional biomolecule nanostructures for cancer therapy
J Wang, Y Li, G Nie - Nature Reviews Materials, 2021 - nature.com
Biomolecule-based nanostructures are inherently multifunctional and harbour diverse
biological activities, which can be explored for cancer nanomedicine. The supramolecular …
biological activities, which can be explored for cancer nanomedicine. The supramolecular …
Bioengineered nanogels for cancer immunotherapy
Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …
Precision cancer sono-immunotherapy using deep-tissue activatable semiconducting polymer immunomodulatory nanoparticles
Nanomedicine holds promise to enhance cancer immunotherapy; however, its potential to
elicit highly specific anti-tumor immunity without compromising immune tolerance has yet to …
elicit highly specific anti-tumor immunity without compromising immune tolerance has yet to …
Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy
Immunometabolic intervention has been applied to treat cancer via inhibition of certain
enzymes associated with intratumoral metabolism. However, small-molecule inhibitors and …
enzymes associated with intratumoral metabolism. However, small-molecule inhibitors and …
Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer
Nanomedicine in combination with immunotherapy offers opportunities to treat cancer in a
safe and effective manner; however, remote control of immune response with spatiotemporal …
safe and effective manner; however, remote control of immune response with spatiotemporal …
The use of alternative strategies for enhanced nanoparticle delivery to solid tumors
M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
decade. Classically, scientists have tried to improve NM delivery by employing passive or …
Immune cell Membrane‐Coated biomimetic nanoparticles for targeted cancer therapy
Nanotechnology has provided great opportunities for managing neoplastic conditions at
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …