Nanocarriers have therapeutic potential to facilitate drug delivery, including biological
agents, small-molecule drugs, and nucleic acids. However, their efficiency is limited by …

To efficiently deliver therapeutics into cancer cells, a number of strategies have been
recently investigated. The toxicity associated with the administration of chemotherapeutic …

Dual-functional liposomes with pH-responsive cell-penetrating peptide (CPP) and active
targeting hyaluronic acid (HA) were fabricated for tumor-targeted drug delivery. A series of …

The design of a non-viral gene delivery vehicle capable of delivering and releasing a
functional nucleic acid cargo intracellularly remains a formidable challenge. For systemic …

A dendritic cells (DCs)-based vaccine (DC-vaccine) system is an attractive technology for
eliciting antigen-specific immune responses that can protect subjects from infectious …

To achieve the promise of stimuli-responsive drug delivery systems for the treatment of
cancer, they should (1) avoid premature clearance;(2) accumulate in tumors and undergo …

Nano-drug/gene delivery systems (DDS) are powerful weapons for the targeted delivery of
various therapeutic molecules in treatment of tumors. Nano systems are being extensively …

The encapsulation of mRNA in nanosystems as gene vaccines for immunotherapy purposes
has experienced an exponential increase in recent years. Despite the many advantages …

Polyrotaxanes (PRXs) are a class of supramolecular threaded macromolecules, in which
cyclic molecules are threaded onto the main-or side-chain of polymers. To date, various …

Nanocarriers are designed to specifically accumulate in diseased tissues. In this context,
targeting of intracellular compartments was shown to enhance the efficacy of many drugs …