B cells, plasma cells and antibody repertoires in the tumour microenvironment

GV Sharonov, EO Serebrovskaya… - Nature Reviews …, 2020 - nature.com
Recent data show that B cells and plasma cells located in tumours or in tumour-draining
lymph nodes can have important roles in shaping antitumour immune responses. In tumour …

Immunosuppressive mechanisms of regulatory B cells

D Catalán, MA Mansilla, A Ferrier, L Soto… - Frontiers in …, 2021 - frontiersin.org
Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress
immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing …

B cells in multiple sclerosis—from targeted depletion to immune reconstitution therapies

MT Cencioni, M Mattoscio, R Magliozzi… - Nature Reviews …, 2021 - nature.com
Increasing evidence indicates the involvement of B cells in the pathogenesis of multiple
sclerosis (MS), but their precise roles are unclear. In this Review, we provide an overview of …

Immunomodulation by mesenchymal stem cells (MSCs): mechanisms of action of living, apoptotic, and dead MSCs

ARR Weiss, MH Dahlke - Frontiers in immunology, 2019 - frontiersin.org
Expectations on mesenchymal stem cell (MSC) treatment are high, especially in the fields of
sepsis, transplant medicine, and autoimmune diseases. Various pre-clinical studies have …

[HTML][HTML] Microbiota-derived metabolites suppress arthritis by amplifying aryl-hydrocarbon receptor activation in regulatory B cells

EC Rosser, CJM Piper, DE Matei, PA Blair… - Cell metabolism, 2020 - cell.com
The differentiation of IL-10-producing regulatory B cells (Bregs) in response to gut-
microbiota-derived signals supports the maintenance of tolerance. However, whether …

Next-generation regulatory T cell therapy

LMR Ferreira, YD Muller, JA Bluestone… - Nature reviews Drug …, 2019 - nature.com
Regulatory T cells (Treg cells) are a small subset of immune cells that are dedicated to
curbing excessive immune activation and maintaining immune homeostasis. Accordingly …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

B cell regulation in cancer and anti-tumor immunity

A Sarvaria, JA Madrigal, A Saudemont - Cellular & molecular …, 2017 - nature.com
The balance between immune effector cells and immunosuppressive cells and how this
regulates the tumor microenvironment has been well described. A significant contribution of …

Regulatory B cells: origin, phenotype, and function

EC Rosser, C Mauri - Immunity, 2015 - cell.com
Regulatory B (Breg) cells are immunosuppressive cells that support immunological
tolerance. Through the production of interleukin-10 (IL-10), IL-35, and transforming growth …

Host response mechanisms in periodontal diseases

N Silva, L Abusleme, D Bravo, N Dutzan… - Journal of Applied Oral …, 2015 - SciELO Brasil
Periodontal diseases usually refer to common inflammatory disorders known as gingivitis
and periodontitis, which are caused by a pathogenic microbiota in the subgingival biofilm …