How to adapt to a changing environment is a fundamental, recurrent problem confronting
cells. One solution is for cells to organize their constituents into a limited number of spatially …

This review summarizes current knowledge about the mechanisms of timely binding and
dissociation of two nucleoid proteins, IHF and Fis, which play fundamental roles in the …

Transcription is a noisy and stochastic process that produces sibling‐to‐sibling variations in
physiology across a population of genetically identical cells. This pattern of diversity reflects …

Silver-Russell syndrome (SRS) is a heterogeneous disorder characterized by intrauterine
and postnatal growth retardation. HMGA2 variants are a rare cause of SRS and its functional …

Recycling and de-novo deposition of histones during DNA replication is a critical challenge
faced by eukaryotic cells and is coordinated by histone chaperones. Spermatogenesis is …

The recent discovery of nuclear and perinuclear perlecan in annulus fibrosus and nucleus
pulposus cells and its known matrix stabilizing properties in tissues introduces the possibility …

In this article we describe the bacterial growth cycle as a closed, self-reproducing, or
autopoietic circuit, reestablishing the physiological state of stationary cells initially inoculated …

The development of chemoresistance reduces the efficacy of anti‐cancer drugs. Cervical
cancer is still one of the most common cancer types in developing countries. The oncogenic …

Some proteins, like the lac repressor (LacI), mediate long-range loops that alter DNA
topology and create torsional barriers. During transcription, RNA polymerase generates …

The nucleoid-associated protein GapR found in Caulobacter crescent us is crucial for DNA
replication, transcription, and cell division. Associated with overtwisted DNA in front of …