Ischemia—Reperfusion injury of the intestine is a significant problem in abdominal aortic
aneurysm surgery, small bowel transplantation, cardiopulmonary bypass, strangulated …

Objective The effects of interleukin (IL)-6 in the injured patient are examined in an attempt to
clarify the potential pathophysiologic role of IL-6 in the response to injury. Summary …

To better define the epidemiology of postinjury multiple organ failure (MOF), we
prospectively evaluated 457 high-risk trauma patients who survived more than 48 hours …

Hypothesis Normal resuscitation (oxygen delivery index [DO 2 I]≥ 500 mL/min per square
meter), compared with supranormal trauma resuscitation (DO 2 I≥ 600 mL/min per square …

The recent history, indications, physiologic objectives, and technical aspects of staged
laparotomy are discussd in this overview. While postinjury refractory coagulopathy is the …

Provision of enteral nutrition (EN) to critically ill patients early upon admission to the
intensive care unit exerts a beneficial physiologic effect that downregulates systemic …

Background: A significant body of clinical literature demonstrates that enteral feeding
significantly reduces the incidence of pneumonia compared to patients fed parenterally. An …

Despite intensive investigation, the pathogenesis of postinjury multiple organ failure (MOF)
remains elusive. Laboratory and clinical research strongly implicate that the gastrointestinal …

A great deal has been learned about the pathophysiologic condition of hemorrhagic shock.
The response of the hormonal and inflammatory mediator systems in patients in …

Objective: Acute mesenteric ischemia is a rare disease entity associated with high morbidity
and mortality. Disparate etiologies and nonspecific symptoms make the diagnosis …