Immunosuppressive drugs in kidney transplantation: impact on patient survival, and incidence of cardiovascular disease, malignancy and infection

R Marcén - Drugs, 2009 - Springer
Renal transplant recipients have increased mortality rates when compared with the general
population. The new immunosuppressive drugs have improved short-term patient survival …

Treatment of polyomavirus infection in kidney transplant recipients: a systematic review

O Johnston, D Jaswal, JS Gill, S Doucette… - …, 2010 - journals.lww.com
Background. Polyomavirus-associated nephropathy (PVAN) is an important cause of kidney
graft loss but there is no consensus on its management. This study aimed to systematically …

BK polyomavirus in solid organ transplantation—Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

HH Hirsch, PS Randhawa… - Clinical …, 2019 - Wiley Online Library
The present AST‐IDCOP guidelines update information on BK polyomavirus (BKP yV)
infection, replication, and disease, which impact kidney transplantation (KT), but rarely non …

[HTML][HTML] Reducing immunosuppression preserves allograft function in presumptive and definitive polyomavirus-associated nephropathy

S Schaub, HH Hirsch, M Dickenmann, J Steiger… - American Journal of …, 2010 - Elsevier
Early detection of polyomavirus BK (BKV) viremia and reduction of immunosuppression is
recommended for preventing polyomavirus-associated nephropathy (Py-VAN), but …

The decade of polyomavirus BK-associated nephropathy: state of affairs

E Ramos, CB Drachenberg, R Wali, HH Hirsch - Transplantation, 2009 - journals.lww.com
In the last 10 years, better immunosuppression drugs have decreased the rates of acute
rejection in kidney transplantation but have also led to the emergence of polyomavirus …

[HTML][HTML] BK virus in solid organ transplant recipients

HH Hirsch, P Randhawa… - American Journal of …, 2009 - Elsevier
The human polyomavirus BK (BKV) is linked to two major complications in transplant
recipients, polyomavirus-associated nephropathy (PyVAN)(1, 2, 3, 4) and polyomavirus …

Mycophenolate mofetil: effects on cellular immune subsets, infectious complications, and antimicrobial activity

ML Ritter, L Pirofski - Transplant Infectious Disease, 2009 - Wiley Online Library
Mycophenolate mofetil (MMF) is one of the most frequently used immunosuppressive drugs
in solid organ transplant recipients. MMF is an inhibitor of inosine‐5′‐monophosphate, and …

Treatment for BK virus: incidence, risk factors and outcomes for kidney transplant recipients in the United States

JD Schold, S Rehman, LK Kayler… - Transplant …, 2009 - Wiley Online Library
There has been a notable rise of BK virus among kidney transplant recipients. Single‐center
reports have identified risk factors for development of BK virus. However, there has not been …

The second international consensus guidelines on the management of BK polyomavirus in kidney transplantation

CN Kotton, N Kamar, D Wojciechowski, M Eder… - …, 2024 - journals.lww.com
BK polyomavirus (BKPyV) remains a significant challenge after kidney transplantation.
International experts reviewed current evidence and updated recommendations according …

Management of polyomavirus-associated nephropathy in renal transplant recipients

DRJ Kuypers - Nature Reviews Nephrology, 2012 - nature.com
Polyomavirus-associated nephropathy (PVAN) remains an important infectious complication
after renal transplantation, affecting 1–10% of recipients and causing graft loss in …