Disturbed balance of inhibitory signaling links hearing loss and cognition

M Knipper, W Singer, K Schwabe… - Frontiers in Neural …, 2022 - frontiersin.org
Neuronal hyperexcitability in the central auditory pathway linked to reduced inhibitory
activity is associated with numerous forms of hearing loss, including noise damage, age …

[HTML][HTML] Multimodal assessment of the GABA system in patients with fragile-X syndrome and neurofibromatosis of type 1

A Lacroix, M Proteau-Lemieux, S Côté, J Near… - Neurobiology of …, 2022 - Elsevier
Fragile-X syndrome (FXS) and Neurofibromatosis of type 1 (NF-1) are two monogenic
disorders sharing neurobehavioral symptoms and pathophysiological mechanisms. Namely …

Deletion of BDNF in Pax2 lineage-derived interneuron precursors in the hindbrain hampers the proportion of excitation/inhibition, learning, and behavior

P Eckert, P Marchetta, MK Manthey… - Frontiers in Molecular …, 2021 - frontiersin.org
Numerous studies indicate that deficits in the proper integration or migration of specific
GABAergic precursor cells from the subpallium to the cortex can lead to severe cognitive …

Acute deletion of the central MR/GR steroid receptor correlates with changes in LTP, auditory neural gain, and GC-A cGMP signaling

D Calis, M Hess, P Marchetta, W Singer… - Frontiers in molecular …, 2023 - frontiersin.org
The complex mechanism by which stress can affect sensory processes such as hearing is
still poorly understood. In a previous study, the mineralocorticoid (MR) and/or glucocorticoid …

Spatial Distribution of Inhibitory Innervations of Excitatory Pyramidal Cells by Major Interneuron Subtypes in the Auditory Cortex

W Zhong, W Zheng, X Ji - Bioengineering, 2023 - mdpi.com
Mental disorders, characterized by the National Institute of Mental Health as disruptions in
neural circuitry, currently account for 13% of the global incidence of such disorders. An …