Intrahepatic cholestasis of pregnancy

C Williamson, V Geenes - Obstetrics & Gynecology, 2014 - journals.lww.com
Intrahepatic cholestasis of pregnancy is the most common pregnancy-specific liver disease
that typically presents in the third trimester. The clinical features are maternal pruritus in the …

Pregnancy and liver disease

RH Westbrook, G Dusheiko… - Journal of …, 2016 - journal-of-hepatology.eu
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[PDF][PDF] Association of severe intrahepatic cholestasis of pregnancy with adverse pregnancy outcomes: a prospective population‐based case‐control study

V Geenes, LC Chappell, PT Seed, PJ Steer… - …, 2014 - Wiley Online Library
Intrahepatic cholestasis of pregnancy (ICP) is a pregnancy‐specific liver disease,
characterized by maternal pruritus and raised serum bile acids. Our objectives were to …

Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis

C Ovadia, J Sajous, PT Seed, K Patel… - The lancet …, 2021 - thelancet.com
Background Ursodeoxycholic acid is commonly used to treat intrahepatic cholestasis of
pregnancy, yet its largest trial detected minimal benefit for a composite outcome (stillbirth …

Reproductive health and liver disease: practice guidance by the American Association for the Study of Liver Diseases

M Sarkar, CW Brady, J Fleckenstein, KA Forde… - …, 2021 - Wiley Online Library
This first Practice Guidance on Reproductive Health from the American Association for the
Study of Liver Diseases (AASLD) is intended to be a comprehensive reference on …

The pathophysiology of intrahepatic cholestasis of pregnancy

PH Dixon, C Williamson - Clinics and Research in Hepatology and …, 2016 - Elsevier
A number of liver disorders are specific to pregnancy. Amongst these, intrahepatic
cholestasis of pregnancy (ICP), also known as obstetric cholestasis (OC), is the commonest …

EASL Clinical Practice Guidelines on the management of liver diseases in pregnancy

C Williamson, M Nana, L Poon, L Kupcinskas… - Journal of …, 2023 - Elsevier
Liver diseases in pregnancy comprise both gestational liver disorders and acute and chronic
hepatic disorders occurring coincidentally in pregnancy. Whether related to pregnancy or …

Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals

CM Ripplinger, AV Glukhov, MW Kay… - American Journal …, 2022 - journals.physiology.org
Cardiac arrhythmias are a major cause of morbidity and mortality worldwide. Although
recent advances in cell-based models, including human-induced pluripotent stem cell …

Ursodeoxycholic acid versus placebo, and early term delivery versus expectant management, in women with intrahepatic cholestasis of pregnancy: semifactorial …

LC Chappell, V Gurung, PT Seed, J Chambers… - Bmj, 2012 - bmj.com
Objectives To test whether ursodeoxycholic acid reduces pruritus in women with intrahepatic
cholestasis of pregnancy, whether early term delivery does not increase the incidence of …

[HTML][HTML] Fetal cardiac dysfunction in intrahepatic cholestasis of pregnancy is associated with elevated serum bile acid concentrations

T Vasavan, S Deepak, IA Jayawardane, M Lucchini… - Journal of …, 2021 - Elsevier
Background & Aims Intrahepatic cholestasis of pregnancy (ICP) is associated with an
increased risk of stillbirth. This study aimed to assess the relationship between bile acid …