The ability to simultaneously image the spatiotemporal activity signatures from many
neurons during unrestrained vertebrate behaviors has become possible through the …

The past decade has witnessed remarkable advances in the simultaneous measurement of
neuronal activity across many brain regions, enabling fundamentally new explorations of the …

Self-organizing neural organoids represent a promising in vitro platform with which to model
human development and disease,,,–. However, organoids lack the connectivity that exists in …

Elevated dopamine transmission in psychosis is assumed to unbalance striatal output
through D1-and D2-receptor-expressing spiny-projection neurons (SPNs). Antipsychotic …

Fiber photometry enables recording of population neuronal calcium dynamics in awake
mice. While the popularity of fiber photometry has grown in recent years, it remains unclear …

Animals associate cues with outcomes and update these associations as new information is
presented. This requires the hippocampus, yet how hippocampal neurons track changes in …

Memories of past events can be recalled long after the event, indicating stability. But new
experiences are also integrated into existing memories, indicating plasticity. In the …

Deciding when and whether to move is critical for survival. Loss of dopamine neurons
(DANs) of the substantia nigra pars compacta (SNc) in patients with Parkinson's disease …

Advances in fluorescence microscopy enable monitoring larger brain areas in-vivo with finer
time resolution. The resulting data rates require reproducible analysis pipelines that are …

Social memory consists of two processes: the detection of familiar compared with novel
conspecifics and the detailed recollection of past social episodes. We investigated the …