Six genetic families of the enzyme carbonic anhydrase (CA, EC 4.2. 1.1) were described to
date. Inhibition of CAs has pharmacologic applications in the field of antiglaucoma …

Introduction: The enzyme carbonic anhydrase (CA, EC 4.2. 1.1) is found in numerous
organisms across the tree of life, with seven distinct classes known to date. CA inhibition can …

Polyphenols are potent micronutrients that can be found in large quantities in various food
sources and spices. These compounds, also known as phenolics due to their phenolic …

The genome of the protozoan parasite Plasmodium falciparum, the causative agent of the
most lethal type of human malaria, contains a single gene annotated as encoding a carbonic …

Introduction: Carbonic anhydrases (CAs, EC 4.2. 1.1) exist as five genetically distinct
families (α, β, γ, δ and ζ) in organisms all over the phylogenetic tree. Due to the ubiquity of …

The structural diversity of natural products offers unique opportunities for drug discovery, but
challenges associated with their isolation and screening can hinder the identification of drug …

An expanded set of diversely substituted 1, 2, 4-oxadiazole-containing primary aromatic
sulfonamides was synthesized and tested for inhibition of human carbonic anhydrase I, II, IX …

The α-class carbonic anhydrases (CAs, EC 4.2. 1.1) from the bacterial pathogens Neisseria
gonorrhoeae (NgCAα) and Vibrio cholerae (VchCAα) were investigated for their inhibition by …

Phenols are among the largest and most widely distributed groups of secondary metabolites
within the plant kingdom. They are implicated in multiple and essential physiological …

Long non-coding RNAs (lncRNAs) are classified as a group of transcripts which regulate
various biological processes, such as RNA processing, epigenetic control, and signaling …