Elastin and collagen fibre microstructure of the human aorta in ageing and disease: a review

A Tsamis, JT Krawiec, DA Vorp - Journal of the royal …, 2013 - royalsocietypublishing.org
Aortic disease is a significant cause of death in developed countries. The most common
forms of aortic disease are aneurysm, dissection, atherosclerotic occlusion and ageing …

Biological and physical factors involved in the maturation of arteriovenous fistula for hemodialysis

A Remuzzi, M Bozzetto - Cardiovascular engineering and technology, 2017 - Springer
One of the most important limitations of hemodialysis (HD) treatment is the vascular access
(VA) that is used to connect the patient's blood vessels to the extracorporeal circulation. The …

Modeling mechano-driven and immuno-mediated aortic maladaptation in hypertension

M Latorre, JD Humphrey - Biomechanics and modeling in …, 2018 - Springer
Uncontrolled hypertension is a primary risk factor for diverse cardiovascular diseases and
thus remains responsible for significant morbidity and mortality. Hypertension leads to …

Analysis of solar-thermal power plants with thermal energy storage and solar-hybrid operation strategy

S Giuliano, R Buck, S Eguiguren - 2011 - asmedigitalcollection.asme.org
Selected solar-hybrid power plants for operation in base-load as well as midload were
analyzed regarding supply security (dispatchable power due to hybridization with fossil fuel) …

A multilayered wall model of arterial growth and remodeling

I Karšaj, JD Humphrey - Mechanics of materials, 2012 - Elsevier
Adaptations of large arteries to sustained alterations in hemodynamics that cause changes
in both caliber and stiffness are increasingly recognized as important initiators or indicators …

Computational modeling predicts immuno-mechanical mechanisms of maladaptive aortic remodeling in hypertension

M Latorre, MR Bersi, JD Humphrey - International journal of engineering …, 2019 - Elsevier
Uncontrolled hypertension is a major risk factor for myriad cardiovascular diseases. Among
its many effects, hypertension increases central artery stiffness which in turn is both an …

Experimentally validated microstructural 3D constitutive model of coronary arterial media

Y Hollander, D Durban, X Lu, GS Kassab, Y Lanir - 2011 - asmedigitalcollection.asme.org
Accurate modeling of arterial response to physiological or pathological loads may shed light
on the processes leading to initiation and progression of a number of vascular diseases and …

Toward a multi-scale computational model of arterial adaptation in hypertension: verification of a multi-cell agent based model

BC Thorne, HN Hayenga, JD Humphrey… - Frontiers in …, 2011 - frontiersin.org
Agent-based models (ABMs) represent a novel approach to study and simulate complex
mechano chemo-biological responses at the cellular level. Such models have been used to …

Fault diagnosis of high speed rolling element bearings due to localized defects using response surface method

PK Kankar, SC Sharma, SP Harsha - 2011 - asmedigitalcollection.asme.org
In this paper, fault diagnosis of high speed rolling element bearings due to localized defects
using response surface method has been done. The localized defects as spalls on outer …

Persistent non-homeostatic remodeling of aortic collagen following a brief episode of hypertension: A computational study

L Irons, C Cavinato, JD Humphrey - Journal of the Mechanical Behavior of …, 2023 - Elsevier
The healthy adult aorta exhibits a remarkable homeostatic ability to respond to sustained
changes in hemodynamic loads under many circumstances, but this mechanical …