Osteoarthritis (OA) is a global disease that, despite extensive research, has limited treatment
options. Pet dogs share both an environment and lifestyle attributes with their owners, and a …

Failure of analgesic drugs in clinical development is common. Along with the current
“reproducibility crisis” in pain research, this has led some to question the use of animal …

Disorders of the somatosensory system such as neuropathic pain are common in people
with chronic neurologic and musculoskeletal diseases, yet these conditions remain an …

Background There is a critical need for proven drugs other than non-steroidal anti-
inflammatory drugs for treatment of degenerative joint disease (DJD) pain in dogs …

Osteoarthritis (OA)-associated pain is a leading cause of disability. Central sensitization
(CS), as a result of OA, is recognized as an important facet of human patients' chronic pain …

Objective To outline the role that spontaneous osteoarthritis (OA) in companion animals can
play in translational research and therapeutic pharmacological development. Outline …

Acute pain and peripheral sensitization development after cautery disbudding was
investigated in 33 calves administered preventive multimodal analgesia. The animals were …

Canine neuropathic pain (NeuP) has been poorly investigated. This study aimed to evaluate
the pain burden, sensory profile and inflammatory cytokines in dogs with naturally-occurring …

Introduction The objective of this study was to retrospectively analyze clinical data from a
referral regenerative medicine practice, to investigate the efficacy of autologous …

Abstract Evaluation of the response to externally applied physical stimuli, such as pressure,
heat, or cold is termed quantitative sensory testing (QST). QST may be used to identify and …