CARD11 functions as a key signaling scaffold that controls antigen-induced lymphocyte
activation during the adaptive immune response. Somatic mutations in CARD11 are …

Epidemiological evidence supports an association between cow's milk consumption and the
risk of diffuse large B-cell lymphoma (DLBCL), the most common non-Hodgkin lymphoma …

Antigen receptor signaling to NF-κB, essential for normal lymphocyte activation, is
dysregulated in several types of lymphoma. During normal signaling, the multidomain …

The activation of NF-κB downstream of T cell receptor (TCR) engagement is a key signaling
step required for normal lymphocyte function during the adaptive immune response. During …

Non-Hodgkin lymphoma is the most common malignancy affecting people living with HIV
(PLWH). Among its several subtypes, diffuse large B-cell lymphoma (DLBCL) is an important …

The CARD11 signaling scaffold transmits signaling between antigen receptors on B and T
lymphocytes and the transcription factor NF-κB during the adaptive immune response …

Uveal melanoma (UVM), the most common primary intraocular malignancy, has a high
mortality because of a high propensity to metastasize. Our study analyzed prognostic value …

Several classes of signaling proteins contain autoinhibitory domains that prevent
unwarranted signaling and coordinate the induction of activity in response to external cues …

Diffuse large B-cell lymphoma (DLBCL), the most common type of Non-Hodgkin lymphoma
(NHL), is a highly heterogeneous and aggressive disease. Regardless of this heterogeneity …

Primary breast lymphoma is a rare form of extra-nodal lymphoid neoplasm. The most
common histological type is the diffuse large B-cell lymphoma, which represents 60–80% of …