Diagnostic point-of-care tests in resource-limited settings

PK Drain, EP Hyle, F Noubary… - The Lancet infectious …, 2014 - thelancet.com
The aim of diagnostic point-of-care testing is to minimise the time to obtain a test result,
thereby allowing clinicians and patients to make a quick clinical decision. Because point-of …

Diagnosis of human immunodeficiency virus infection

BS Parekh, CY Ou, PN Fonjungo… - Clinical microbiology …, 2018 - Am Soc Microbiol
SUMMARY HIV diagnostics have played a central role in the remarkable progress in
identifying, staging, initiating, and monitoring infected individuals on life-saving antiretroviral …

Initiating antiretroviral therapy for HIV at a patient's first clinic visit: the RapIT randomized controlled trial

S Rosen, M Maskew, MP Fox, C Nyoni… - PLoS …, 2016 - journals.plos.org
Background High rates of patient attrition from care between HIV testing and antiretroviral
therapy (ART) initiation have been documented in sub-Saharan Africa, contributing to …

Point-of-care HIV viral load testing: an essential tool for a sustainable global HIV/AIDS response

PK Drain, J Dorward, A Bender, L Lillis… - Clinical microbiology …, 2019 - Am Soc Microbiol
The global public health community has set ambitious treatment targets to end the HIV/AIDS
pandemic. With the notable absence of a cure, the goal of HIV treatment is to achieve …

Effect of point-of-care CD4 cell count tests on retention of patients and rates of antiretroviral therapy initiation in primary health clinics: an observational cohort study

IV Jani, NE Sitoe, ER Alfai, PL Chongo, JI Quevedo… - The Lancet, 2011 - thelancet.com
Background Loss to follow-up of HIV-positive patients before initiation of antiretroviral
therapy can exceed 50% in low-income settings and is a challenge to the scale-up of …

Current strategies for improving access and adherence to antiretroviral therapies in resource-limited settings

ML Scanlon, RC Vreeman - HIV/AIDS-Research and Palliative …, 2013 - Taylor & Francis
The rollout of antiretroviral therapy (ART) significantly reduced human immunodeficiency
virus (HIV)-related morbidity and mortality, but good clinical outcomes depend on access …

Microfluidic CD4+ and CD8+ T Lymphocyte Counters for Point-of-Care HIV Diagnostics Using Whole Blood

NN Watkins, U Hassan, G Damhorst, HK Ni… - Science translational …, 2013 - science.org
Roughly 33 million people worldwide are infected with HIV; disease burden is highest in
resource-limited settings. One important diagnostic in HIV disease management is the …

Opportunities and challenges for cost-efficient implementation of new point-of-care diagnostics for HIV and tuberculosis

M Schito, TF Peter, S Cavanaugh… - Journal of Infectious …, 2012 - academic.oup.com
Stakeholders agree that supporting high-quality diagnostics is essential if we are to continue
to make strides in the fight against human immunodeficiency virus (HIV) and tuberculosis …

Integrated prevention of mother-to-child HIV transmission services, antiretroviral therapy initiation, and maternal and infant retention in care in rural north-central …

MH Aliyu, M Blevins, CM Audet, M Kalish, UI Gebi… - The lancet HIV, 2016 - thelancet.com
Background Antiretroviral therapy (ART) and retention in care are essential for the
prevention of mother-to-child HIV transmission (PMTCT). We aimed to assess the effect of a …

Emerging technologies for point-of-care CD4 T-lymphocyte counting

DS Boyle, KR Hawkins, MS Steele, M Singhal… - Trends in …, 2012 - cell.com
A CD4 T-lymphocyte count determines eligibility for antiretroviral therapy (ART) in patients
recently diagnosed with HIV and also monitors the efficacy of ART treatment thereafter. ART …