• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

There is increasing evidence regarding the prevalence of genetic cardiomyopathies, for
which arrhythmias may be the first presentation. Ventricular and atrial arrhythmias …

Background: Filamin C truncating variants (FLNCtv) cause a form of arrhythmogenic
cardiomyopathy: the mode of presentation, natural history, and risk stratification of FLNCtv …

Background Mutations in filamin-C (FLNC) are involved in the pathogenesis of
arrhythmogenic cardiomyopathy (ACM) and dilated cardiomyopathy (DCM), and have been …

The primary etiology of a diverse range of cardiomyopathies is now understood to be
genetic, creating a new paradigm for targeting treatments on the basis of the underlying …

Aims To characterize the phenotype, clinical outcomes and rate of disease progression in
patients with early‐stage non‐ischaemic cardiomyopathy (early‐NICM). Methods and results …

Inherited cardiomyopathies are a major cause of mortality and morbidity worldwide and can
be caused by mutations in a wide range of proteins located in different cellular …

Objective In this study, a risk score for ventricular arrhythmias (VA) were evaluated for
predicting the risk of ventricular arrhythmia (VA) of acute myocardial infarction (AMI) patients …

Background: The FLNC gene has recently garnered attention as a likely cause of
arrhythmogenic cardiomyopathy, which is considered an actionable genetic condition …

BACKGROUND: Variants in RBM20 are reported in 2% to 6% of familial cases of dilated
cardiomyopathy and may be associated with fatal ventricular arrhythmia and rapid heart …