Cyclodextrins are garnering increasing attention because they offer several benefits. For
instance, cyclodextrins can form several complexes and supramolecular structures not only …

Cancer is a severe disease that, in 2022, caused more than 9.89 million deaths worldwide.
One worrisome type of cancer is bone cancer, such as osteosarcoma and Ewing tumors …

Due to the strong tendency towards poorly soluble drugs in modern development pipelines,
enabling drug formulations such as amorphous solid dispersions, cyclodextrins, co-crystals …

Apalutamide (APA), a second-generation nonsteroidal antiandrogen BCS Class II drug with
poor solubility and high permeability. A novel 1: 1 cocrystal of Apalutamide (APA) with …

β-cyclodextrin has a unique annular hollow ultrastructure that allows encapsulation of
various poorly water-soluble drugs in the resulting cavity, thereby increasing drug stability …

Solubility of active pharmaceutical ingredients is an important aspect of drug processing and
formulation. Although caffeine was a subject of many studies aiming to quantify saturated …

The main aims of the study were to disclose the influence of the structure on the solubility,
distribution and permeability of the parent substances, iproniazid (IPN), isoniazid (INZ) and …

Cocrystallization and coamorphization are similar yet independent approaches toward
modifying various pharmaceutically relevant properties of modern drug compounds, in …

Partitioning/distribution and permeability are key parameters determining successful drug
absorption. In the present work the distribution thermodynamics of nortryptiline …

Cyclodextrin-based delivery systems have been intensively used to improve the
bioavailability of drugs through the modification of their pharmaceutically relevant properties …