Oligonucleotide-based therapies are advanced novel interventions used in the management
of various respiratory diseases such as asthma and Chronic Obstructive Pulmonary Disease …

RNA interference (RNAi) is considered a highly specific approach for gene silencing and
holds tremendous potential for treatment of various pathologic conditions such as …

Multisystem inflammatory syndrome in children (MIS-C) is an illness that emerged amidst the
COVID-19 pandemic but shares many clinical features with the pre-pandemic syndrome of …

Among non-viral vectors, chitosan and chitosan derivatives have been developed in vitro
and in vivo for DNA and siRNA delivery systems because of their cationic charge …

Human respiratory syncytial virus (RSV) is a ubiquitous pathogen that infects everyone
worldwide early in life and is a leading cause of severe lower respiratory tract disease in the …

Since the first description of RNA interference (RNAi) in animals less than a decade ago,
there has been rapid progress towards its use as a therapeutic modality against human …

Nanoparticles are materials with overall dimensions in the nanoscale, ie, under 100 nm. In
recent years, these materials have emerged as important players in modern medicine, with …

Achieving efficient in vivo delivery of siRNA to the appropriate target cell would be a major
advance in the use of RNAi in gene function studies and as a therapeutic modality …

The discovery of small noncoding RNAs (sncRNAs) with regulatory functions is a recent
breakthrough in biology. Among sncRNAs, microRNA (miRNA), derived from host or virus …

Biopolymers found in marine animals and plants offer tremendous, largely untapped
pharmaceutical potential. Research shows that these biopolymers can be used to combat …