Activation of aromatic C H bonds by a transition metal catalyst has received significant
attention in the synthetic chemistry community. In recent years, rapid and site‐selective …

Palladium catalysis has achieved the status of an indispensable tool for both common and
state-of-theart organic synthesis. Among basic types of palladium-catalyzed transformations …

Arylraryl bond formation is one of the most important tools of modern organic synthesis.
These bonds are very often found in natural products such as alkaloids as well as in …

The biaryl structural motif is a predominant feature in many pharmaceutically relevant and
biologically active compounds. As a result, for over a century1 organic chemists have sought …

Collectively, palladium‐catalyzed coupling reactions represent some of the most powerful
and versatile tools available to synthetic organic chemists. Their widespread popularity …

In recent years, transition metal‐catalyzed direct (hetero) arylation reactions of heteroarenes
with (hetero) aryl halides and pseudohalides have received significant attention as eco …

Many significant products (drugs, materials, optical devices, etc.) commercialized or in the
development phase, possess aromatic carbon-carbon and aromatic carbonnitrogen bonds …

The concerted metalation− deprotonation mechanism predicts relative reactivity and
regioselectivity for a diverse set of arenes spanning the entire spectrum of known palladium …

During the last two decades there has been considerable growth in the development of
catalytic reactions capable of activating unreactive C–H bonds. These methods allow for the …

Many boronic acids, including 2-heterocyclic, vinyl, and cyclopropyl derivatives, are
inherently unstable, which can limit their benchtop storage and/or efficient cross-coupling …