Heartworm disease due to Dirofilaria immitis continues to cause severe disease and even
death in dogs and other animals in many parts of the world, even though safe, highly …

Filarial nematodes are important helminth parasites of the tropics and a leading cause of
global disability. They include species responsible for onchocerciasis, lymphatic filariasis …

Complete genome DNA sequence and analysis is presented for Wolbachia, the obligate
alpha-proteobacterial endosymbiont required for fertility and survival of the human filarial …

The presence of intracellular bacteria in the body of various species of filarial nematodes,
including important parasites such as Brugia malayi, Dirofilaria immitis, and Onchocerca …

Background Wolbachia is an obligate intracellular maternally transmitted, gram-negative
bacterium which forms a spectrum of endosymbiotic relationships from parasitism to …

More than 150 million humans in tropical countries are infected by filarial nematodes which
harbor intracellular bacterial endosymbionts of the genus Wolbachia (Rickettsiales). These …

Lateral gene transfer and recombination play important roles in the evolution of many
parasitic bacteria. Here we investigate intragenic recombination in Wolbachia bacteria …

Onchocerca volvulus is a tissue-invasive parasitic nematode causing skin and eye
pathology in human onchocerciasis. The filariae habour abundant intracellular Wolbachia …

A safer, more effective adulticidal treatment and a safe method for reducing microfilaremia
and breaking transmission of heartworm disease early in the treatment are needed. The …

Lymphatic filarial nematodes are infected with endosymbiotic Wolbachia bacteria.
Lipopolysaccharide from these bacteria is the major activator of innate inflammatory …