Pathophysiological role of growth differentiation factor 15 (GDF15) in obesity, cancer, and cachexia
JA Siddiqui, R Pothuraju, P Khan, G Sharma… - Cytokine & growth factor …, 2022 - Elsevier
Growth differentiation factor 15 or macrophage inhibitory cytokine-1 (GDF15/MIC-1) is a
divergent member of the transforming growth factor β superfamily and has a diverse …
divergent member of the transforming growth factor β superfamily and has a diverse …
Growth differentiation factor 15 (GDF15) in cancer cell metastasis: from the cells to the patients
A Spanopoulou, V Gkretsi - Clinical & experimental metastasis, 2020 - Springer
Abstract Growth differentiation factor 15 (GDF15), a member of the transforming growth
factor β superfamily, has been postulated to be implicated in cancer cell metastasis although …
factor β superfamily, has been postulated to be implicated in cancer cell metastasis although …
C/EBPβ/AEP signaling regulates the oxidative stress in malignant cancers, stimulating the metastasis
Solid tumors start as a local disease, but some are capable of metastasizing to the lymph
nodes and distant organs. The hypoxic microenvironment, which is critical during cancer …
nodes and distant organs. The hypoxic microenvironment, which is critical during cancer …
Emerging roles for browning of white adipose tissue in prostate cancer malignant behaviour
A Álvarez-Artime, B García-Soler, RM Sainz… - International Journal of …, 2021 - mdpi.com
In addition to its well-known role as an energy repository, adipose tissue is one of the largest
endocrine organs in the organism due to its ability to synthesize and release different …
endocrine organs in the organism due to its ability to synthesize and release different …
[HTML][HTML] PathIN: an integrated tool for the visualization of pathway interaction networks
G Minadakis, K Christodoulou, G Tsouloupas… - Computational and …, 2023 - Elsevier
PathIN is a web-service that provides an easy and flexible way for rapidly creating pathway-
based networks at several functional biological levels: genes, compounds and reactions …
based networks at several functional biological levels: genes, compounds and reactions …
Protein signatures to distinguish aggressive from indolent prostate cancer
Background Distinguishing men with aggressive from indolent prostate cancer is critical to
decisions in the management of clinically localized prostate cancer. Molecular signatures of …
decisions in the management of clinically localized prostate cancer. Molecular signatures of …
Ras suppressor 1 long form (RSU1L) silencing promotes apoptosis in invasive breast cancer cells
Abstract Ras Suppressor-1 (RSU1) is a cell-extracellular matrix (ECM) adhesion protein
implicated in breast cancer (BC) cell metastasis. Nevertheless, its role in apoptosis is yet …
implicated in breast cancer (BC) cell metastasis. Nevertheless, its role in apoptosis is yet …
ILK silencing inhibits migration and invasion of more invasive glioblastoma cells by downregulating ROCK1 and Fascin-1
Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor and it is
associated with poor survival. Integrin-linked kinase (ILK) is a serine/threonine protein …
associated with poor survival. Integrin-linked kinase (ILK) is a serine/threonine protein …
Antitumor potential of dark sweet cherry sweet (Prunus avium) phenolics in suppressing xenograft tumor growth of MDA-MB-453 breast cancer cells
This study investigated in vivo the antitumor activity of dark sweet cherry (DSC) whole
extracted phenolics (WE) and fractions enriched in anthocyanins (ACN) or …
extracted phenolics (WE) and fractions enriched in anthocyanins (ACN) or …
Depletion of Ras Suppressor-1 (RSU-1) promotes cell invasion of breast cancer cells through a compensatory upregulation of a truncated isoform
Extracellular matrix (ECM)-adhesion proteins and actin cytoskeleton are pivotal in cancer
cell invasion. Ras Suppressor-1 (RSU-1), a cell-ECM adhesion protein that interacts with …
cell invasion. Ras Suppressor-1 (RSU-1), a cell-ECM adhesion protein that interacts with …