Current research therapeutic strategies for Alzheimer's disease treatment

J Folch, D Petrov, M Ettcheto, S Abad… - Neural …, 2016 - Wiley Online Library
Alzheimer's disease (AD) currently presents one of the biggest healthcare issues in the
developed countries. There is no effective treatment capable of slowing down disease …

Dysfunction of the neurovascular unit in ischemic stroke and neurodegenerative diseases: an aging effect

W Cai, K Zhang, P Li, L Zhu, J Xu, B Yang, X Hu… - Ageing research …, 2017 - Elsevier
Current understanding on the mechanisms of brain injury and neurodegeneration highlights
an appreciation of multicellular interactions within the neurovascular unit (NVU), which …

ESPEN guidelines on nutrition in dementia

D Volkert, M Chourdakis, G Faxen-Irving, T Frühwald… - Clinical nutrition, 2015 - Elsevier
Background Older people suffering from dementia are at increased risk of malnutrition due
to various nutritional problems, and the question arises which interventions are effective in …

[HTML][HTML] Plasma nutrient status of patients with Alzheimer's disease: systematic review and meta-analysis

SL da Silva, B Vellas, S Elemans, J Luchsinger… - Alzheimer's & …, 2014 - Elsevier
Background Alzheimer disease (AD) patients are at risk of nutritional insufficiencies because
of physiological and psychological factors. Nutritional compounds are postulated to play a …

Position of the Academy of Nutrition and Dietetics: food and nutrition for older adults: promoting health and wellness

M Bernstein, N Munoz - Journal of the Academy of Nutrition and Dietetics, 2012 - Elsevier
It is the position of the Academy of Nutrition and Dietetics that all Americans aged 60 years
and older receive appropriate nutrition care; have access to coordinated, comprehensive …

Efficacy of Souvenaid in mild Alzheimer's disease: results from a randomized, controlled trial

P Scheltens, JWR Twisk, R Blesa… - Journal of …, 2012 - content.iospress.com
Souvenaid aims to improve synapse formation and function. An earlier study in patients with
Alzheimer's disease (AD) showed that Souvenaid increased memory performance after 12 …

Preventing dementia? Interventional approaches in mild cognitive impairment

V Lissek, B Suchan - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Mild cognitive impairment (MCI) is defined as an intermediate state between normal
cognitive aging and dementia. It describes a status of the subjective impression of cognitive …

[HTML][HTML] Curcumin and Apigenin–novel and promising therapeutics against chronic neuroinflammation in Alzheimer's disease

M Venigalla, E Gyengesi, G Münch - Neural regeneration …, 2015 - journals.lww.com
Alzheimer's disease is a progressive neurodegenerative disorder, characterized by
deposition of amyloid beta, neurofibrillary tangles, astrogliosis and microgliosis, leading to …

[HTML][HTML] Nutrition for the ageing brain: towards evidence for an optimal diet

D Vauzour, M Camprubi-Robles… - Ageing research …, 2017 - Elsevier
As people age they become increasingly susceptible to chronic and extremely debilitating
brain diseases. The precise cause of the neuronal degeneration underlying these disorders …

[HTML][HTML] Omega-3 fatty acid status enhances the prevention of cognitive decline by B vitamins in mild cognitive impairment

A Oulhaj, F Jernerén, H Refsum… - Journal of …, 2016 - content.iospress.com
A randomized trial (VITACOG) in people with mild cognitive impairment (MCI) found that B
vitamin treatment to lower homocysteine slowed the rate of cognitive and clinical decline …