Rapid cortical plasticity supports long-term memory formation

M Hebscher, E Wing, J Ryan, A Gilboa - Trends in Cognitive Sciences, 2019 - cell.com
The standard systems consolidation account posits that recently formed memories are
initially dependent on the hippocampus and only gradually become instantiated in …

Presynaptic AMPA receptors in health and disease

L Zanetti, M Regoni, E Ratti, F Valtorta, J Sassone - Cells, 2021 - mdpi.com
AMPA receptors (AMPARs) are ionotropic glutamate receptors that play a major role in
excitatory neurotransmission. AMPARs are located at both presynaptic and postsynaptic …

Increased expression of schizophrenia-associated gene C4 leads to hypoconnectivity of prefrontal cortex and reduced social interaction

AL Comer, T Jinadasa, B Sriram, RA Phadke… - PLoS …, 2020 - journals.plos.org
Schizophrenia is a severe mental disorder with an unclear pathophysiology. Increased
expression of the immune gene C4 has been linked to a greater risk of developing …

[HTML][HTML] Cognitive outcomes caused by low-level lead, cadmium, and mercury mixture exposure at distinct phases of brain development

L Ouyang, Q Li, S Rao, R Su, Y Zhu, G Du, J Xie… - Food and Chemical …, 2023 - Elsevier
Contaminated water and food are the main sources of lead, cadmium, and mercury in the
human body. Long-term and low-level ingestion of these toxic heavy metals may affect brain …

EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons

SS Parker, KT Ly, AD Grant, J Sweetland… - Journal of Cell …, 2023 - rupress.org
Dendritic spines are the postsynaptic compartment of a neuronal synapse and are critical for
synaptic connectivity and plasticity. A developmental precursor to dendritic spines, dendritic …

Microscale neuronal activity collectively drives chaotic and inflexible dynamics at the macroscale in seizures

DRW Burrows, G Diana, B Pimpel… - Journal of …, 2023 - Soc Neuroscience
Neuronal activity propagates through the network during seizures, engaging brain dynamics
at multiple scales. Such propagating events can be described through the avalanches …

Maternal immune activation and schizophrenia–evidence for an immune priming disorder

Z Choudhury, B Lennox - Frontiers in Psychiatry, 2021 - frontiersin.org
Schizophrenia is a complex neurodevelopmental disorder affecting around 19. 8 million
people worldwide. The etiology of the disorder is due to many interacting genetic and …

Neuronal glycoprotein M6a: an emerging molecule in chemical synapse formation and dysfunction

A León, GI Aparicio, C Scorticati - Frontiers in Synaptic Neuroscience, 2021 - frontiersin.org
The cellular and molecular mechanisms underlying neuropsychiatric and
neurodevelopmental disorders show that most of them can be categorized as …

Invaginating structures in mammalian synapses

RS Petralia, YX Wang, MP Mattson… - Frontiers in synaptic …, 2018 - frontiersin.org
Invaginating structures at chemical synapses in the mammalian nervous system exist in
presynaptic axon terminals, postsynaptic spines or dendrites, and glial processes. These …

Dendritic spines: synaptogenesis and synaptic pruning for the developmental organization of brain circuits

Z Petanjek, I Banovac, D Sedmak, A Hladnik - Dendritic spines: structure …, 2023 - Springer
Synaptic overproduction and elimination is a regular developmental event in the mammalian
brain. In the cerebral cortex, synaptic overproduction is almost exclusively correlated with …