Monkeypox: a review of epidemiological modelling studies and how modelling has led to mechanistic insight

M Banuet-Martinez, Y Yang, B Jafari, A Kaur… - Epidemiology & …, 2023 - cambridge.org
Human monkeypox (mpox) virus is a viral zoonosis that belongs to the Orthopoxvirus genus
of the Poxviridae family, which presents with similar symptoms as those seen in human …

[HTML][HTML] Modelling how increased Cathepsin B/L and decreased TMPRSS2 usage for cell entry by the SARS-CoV-2 Omicron variant may affect the efficacy and …

P Padmanabhan, NM Dixit - Journal of Theoretical Biology, 2023 - Elsevier
Abstract The SARS-CoV-2 Omicron variant harbours many mutations in its spike protein
compared to the original SARS-CoV-2 strain, which may alter its ability to enter cells, cell …

How robust are estimates of key parameters in standard viral dynamic models?

C Zitzmann, R Ke, RM Ribeiro… - PLOS Computational …, 2024 - journals.plos.org
Mathematical models of viral infection have been developed, fitted to data, and provide
insight into disease pathogenesis for multiple agents that cause chronic infection, including …

Determination of significant immunological timescales from mRNA-LNP-based vaccines in humans

IR Moyles, CS Korosec, JM Heffernan - Journal of Mathematical Biology, 2023 - Springer
A compartment model for an in-host liquid nanoparticle delivered mRNA vaccine is
presented. Through non-dimensionalisation, five timescales are identified that dictate the …

Within-host evolution of SARS-CoV-2: how often are de novo mutations transmitted from symptomatic infections?

CS Korosec, LM Wahl, JM Heffernan - Virus Evolution, 2024 - academic.oup.com
Despite a relatively low mutation rate, the large number of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infections has allowed for substantial genetic …

SARS-CoV-2 booster vaccine dose significantly extends humoral immune response half-life beyond the primary series

CS Korosec, DW Dick, IR Moyles, J Watmough - Scientific Reports, 2024 - nature.com
SARS-CoV-2 lipid nanoparticle mRNA vaccines continue to be administered as the
predominant prophylactic measure to reduce COVID-19 disease pathogenesis. Quantifying …

[PDF][PDF] New Challenges in the Mathematical Modelling and Control of COVID-19 Epidemics: Analysis of Non-Pharmaceutical Actions and Vaccination Strategies

CM Verrelli, F Della Rossa - Mathematics, 2024 - mdpi.com
Since its official appearance in China in December 2019, COVID-19 (SARS-CoV-2)
immediately reached pandemic proportions on six continents and in over 195 countries. It …

Within-host evolution of SARS-CoV-2: how often are mutations transmitted?

CS Korosec, LM Wahl, JM Heffernan - bioRxiv, 2023 - biorxiv.org
Despite a relatively low mutation rate, the large number of SARS-CoV-2 infections has
allowed for substantial genetic change, leading to a multitude of emerging variants. Using a …