Cancer chemotherapy and radiotherapy are designed to kill cancer cells mostly by inducing
DNA damage. DNA damage is normally recognized and repaired by the intrinsic DNA …

Background: Metastasis is the most common cause of disease failure and mortality for non-
small cell lung cancer (NSCLC) after surgical resection. Snail and TWIST1 are epithelial …

The epithelial–mesenchymal transition (EMT), one of the main mechanisms underlying
development of cancer metastasis, induces stem-like properties in epithelial cells. Bmi1 is a …

Epithelial–mesenchymal transition (EMT) is a pivotal mechanism for cancer dissemination.
However, EMT-regulated individual cancer cell invasion is difficult to detect in clinical …

BACKGROUND & AIMS: Some cancer cells have activities that are similar to those of stem
cells from normal tissues, and cell dedifferentiation correlates with poor prognosis. Little is …

Adenomyosis is an oestrogen‐dependent disease caused by a downward extension of the
endometrium into the uterine myometrium. Epithelial–mesenchymal transition (EMT) …

Background The HSP70 family of heat shock protein plays a critical role in protein synthesis
and transport to maintain protein homeostasis. Several studies have indicated that HSP70s …

We identified a novel gene HJURP (Holliday junction–recognizing protein) whose activation
seemed to play a pivotal role in the immortality of cancer cells. HJURP was considered a …

Purpose: We investigated the mechanism and clinical significance of the epithelial-
mesenchymal transition (EMT)-induced chemoresistance in head and neck squamous cell …

Major causes of head and neck squamous cell carcinoma (HNSCC)-related deaths are
cervical node and distant metastasis. We previously demonstrated that overexpression of …