Transfer RNAs (tRNAs) play pivotal roles in the transmission of genetic information, and
abnormality of tRNAs directly leads to translation disorders and causes diseases, including …

As the central dogma of molecular biology, genetic information flows from DNA through
transcription into RNA followed by translation of the message into protein by transfer RNAs …

Recent advancements have illuminated the critical role of RNA modifications in post-
transcriptional regulation, shaping the landscape of gene expression. This review explores …

Thiolation of uridine 34 in the anticodon loop of several tRNAs is conserved in the three
domains of life and guarantees fidelity of protein translation. U34-tRNA thiolation is …

Glioblastoma heterogeneity and plasticity remain controversial, with proposed subtypes
representing the average of highly heterogeneous admixtures of independent transcriptional …

Kti12 and PSTK are closely related and highly similar proteins implicated in different aspects
of tRNA metabolism. Kti12 has been identified as an essential regulatory factor of the …

Highly pathogenic coronaviruses, including SARS‐CoV‐2, SARS‐CoV and MERS‐CoV, are
thought to be transmitted from bats to humans, but the viral genetic signatures that contribute …

Viruses are common causes of various diseases. These pathogens are nanometer-size
infectious particles that replicate inside the viable cells of an organism and depend on host …