Despite advances in our understanding of the pathophysiology and the management of
pulmonary arterial hypertension (PAH), significant therapeutic gaps remain for this …

Abstract Resveratrol, trans 3, 5, 4′-trihydroxystilbene, is a stilbenoid polyphenol with a wide
range of properties including antioxidant, neuroprotective, cardioprotective, anti …

Rationale: The pathogenesis of pulmonary arterial hypertension (PAH) remains unclear. The
4 microRNAs representing the miR-143 and miR-145 stem loops are genomically clustered …

Women with pulmonary arterial hypertension (PAH) exhibit better right ventricular (RV)
function and survival than men; however, the underlying mechanisms are unknown. We …

Pulmonary arterial hypertension (PAH) is a devastating and progressive disease with
marked morbidity and mortality. Even though being female represents one of the most …

Importance Pulmonary arterial hypertension (PAH) is characterized by severe remodeling of
the distal pulmonary arteries, increased pulmonary vascular resistance, and right ventricular …

Abstract Background Cardiovascular diseases (CVDs) culminating into heart failure (HF) are
major causes of death in men and women. Prevalence and manifestation, however, differ …

Estrogens are disease modifiers in PAH. Even though female patients exhibit better right
ventricular (RV) function than men, estrogen effects on RV function (a major determinant of …

Background Women are more susceptible than men to several forms of pulmonary
hypertension, but have better survival. Sparse data are available on chronic thromboembolic …

Recently a great deal of progress has been made in our understanding of pulmonary
hypertension (PH). Research from the past 30 years has resulted in newer treatments that …