Epithelial to mesenchymal transition (EMT) is a process during which cells lose their
epithelial characteristics, for instance cell polarity and cell–cell contact, and gain …

Tumor metastasis is a multi-step process by which tumor cells disseminate from their primary
site and form secondary tumors at a distant site. And metastasis is the major cause of death …

Cancer-associated fibroblasts (CAFs) play a pivotal role in regulating tumour progression.
Therefore, understanding how CAFs communicate with hepatocellular carcinoma (HCC) is …

Background Metastasis is a major cause of death in human colorectal cancer patients.
However, the contribution of chemokines in the tumor microenvironment to tumor metastasis …

Background MicroRNAs are stable and easy to detect in plasma. The plasma levels of
microRNAs are often changed in disease conditions, including cancer. This makes …

The small GTPase Rac1 has been implicated in a variety of dynamic cell biological
processes, including cell proliferation, cell survival, cell-cell contacts, epithelial …

Infants who are exclusively breastfed in the first six months of age receive adequate
nutrients, achieving optimal immune protection and growth. In addition to the known …

As a new class of non-coding RNA, circular RNAs (circRNAs) play crucial roles in the
development and progression of various cancers. However, the detailed functions of …

Abstract miR-320 expression level is found to be down-regulated in human colon cancer. To
date, however, its underlying mechanisms in the chemo-resistance remain largely unknown …

Background & Aims Cancer cells alter glucose metabolism to support their uncontrolled
proliferation. Changes in microRNAs (miRNAs) have been associated with colorectal cancer …