Engineering whole-cell microbial biosensors: Design principles and applications in monitoring and treatment of heavy metals and organic pollutants

C Liu, H Yu, B Zhang, S Liu, C Liu, F Li, H Song - Biotechnology Advances, 2022 - Elsevier
Biosensors have been widely used as cost-effective, rapid, in situ, and real-time analytical
tools for monitoring environments. The development of synthetic biology has enabled …

[HTML][HTML] Machine learning for biochemical engineering: A review

M Mowbray, T Savage, C Wu, Z Song, BA Cho… - Biochemical …, 2021 - Elsevier
The field of machine learning is comprised of techniques, which have proven powerful
approaches to knowledge discovery and construction of 'digital twins' in the highly …

Hyenadna: Long-range genomic sequence modeling at single nucleotide resolution

E Nguyen, M Poli, M Faizi, A Thomas… - Advances in neural …, 2024 - proceedings.neurips.cc
Genomic (DNA) sequences encode an enormous amount of information for gene regulation
and protein synthesis. Similar to natural language models, researchers have proposed …

Nucleotide Transformer: building and evaluating robust foundation models for human genomics

H Dalla-Torre, L Gonzalez, J Mendoza-Revilla… - Nature …, 2024 - nature.com
The prediction of molecular phenotypes from DNA sequences remains a longstanding
challenge in genomics, often driven by limited annotated data and the inability to transfer …

Big bird: Transformers for longer sequences

M Zaheer, G Guruganesh, KA Dubey… - Advances in neural …, 2020 - proceedings.neurips.cc
Transformers-based models, such as BERT, have been one of the most successful deep
learning models for NLP. Unfortunately, one of their core limitations is the quadratic …

DNABERT: pre-trained Bidirectional Encoder Representations from Transformers model for DNA-language in genome

Y Ji, Z Zhou, H Liu, RV Davuluri - Bioinformatics, 2021 - academic.oup.com
Motivation Deciphering the language of non-coding DNA is one of the fundamental
problems in genome research. Gene regulatory code is highly complex due to the existence …

BERT-Promoter: An improved sequence-based predictor of DNA promoter using BERT pre-trained model and SHAP feature selection

NQK Le, QT Ho, VN Nguyen, JS Chang - Computational Biology and …, 2022 - Elsevier
A promoter is a sequence of DNA that initializes the process of transcription and regulates
whenever and wherever genes are expressed in the organism. Because of its importance in …

iPro-WAEL: a comprehensive and robust framework for identifying promoters in multiple species

P Zhang, H Zhang, H Wu - Nucleic Acids Research, 2022 - academic.oup.com
Promoters are consensus DNA sequences located near the transcription start sites and they
play an important role in transcription initiation. Due to their importance in biological …

[图书][B] Representation learning for natural language processing

Z Liu, Y Lin, M Sun - 2023 - library.oapen.org
This book provides an overview of the recent advances in representation learning theory,
algorithms, and applications for natural language processing (NLP), ranging from word …

De novo domestication of wild species to create crops with increased resilience and nutritional value

K Gasparini, J dos Reis Moreira, LEP Peres… - Current Opinion in Plant …, 2021 - Elsevier
Creating crops with resistance to drought, soil salinity and insect damage, that
simultaneously have higher nutritional quality, is challenging to conventional breeding due …