The transient receptor potential (TRP) multigene superfamily encodes integral membrane
proteins that function as ion channels. Members of this family are conserved in yeast …

Congenital stationary night blindness (CSNB) refers to a group of genetically and clinically
heterogeneous retinal disorders. Seventeen different genes with more than 360 different …

Transient receptor potential (TRP) cation channels have been among the most aggressively
pursued drug targets over the past few years. Although the initial focus of research was on …

We report a high-quality draft sequence of the genome of the horse (Equus caballus). The
genome is relatively repetitive but has little segmental duplication. Chromosomes appear to …

Polar bears (PBs) are superbly adapted to the extreme Arctic environment and have become
emblematic of the threat to biodiversity from global climate change. Their divergence from …

Ion channels of the Transient Receptor Potential (TRP) family mediate the influx of
monovalent and/or divalent cations into cells in response to a host of chemical or physical …

During the last decade, coat colouration in mammals has been investigated in numerous
studies. Most of these studies addressing the genetics of coat colouration were on …

Transient receptor potential (TRP) channels are a widely expressed family of 28
evolutionarily conserved cationic ion channels that operate as primary detectors of chemical …

The ON pathway of the visual system, which detects increases in light intensity, is
established at the first retinal synapse between photoreceptors and ON-bipolar cells …

An essential step in intricate visual processing is the segregation of visual signals into ON
and OFF pathways by retinal bipolar cells (BCs). Glutamate released from photoreceptors …