Chronic inflammation participates in the progression of multiple chronic diseases, including
obesity, diabetes mellitus (DM), and DM related complications. Diabetic ulcer, characterized …

The development of biological methods over the past decade has stimulated great interest in
the possibility to regenerate human tissues. Advances in stem cell research, gene therapy …

Introduction Cell therapy with mesenchymal stem cells (MSCs) and biomaterials holds great
potential for the treatment of diabetic ulceration; however, the underlying mechanism as well …

Impaired wound healing presents great health risks to patients. While encouraging, the
current clinical successes of mesenchymal stromal cell (MSC)-based therapies for tissue …

Introduction Full-thickness skin wound healing remains a serious undertaking for patients.
While stem cell-derived exosomes have been proposed as a potential therapeutic approach …

Progressive peripheral arterial disease (PAD) can result in chronic limb-threatening
ischemia (CLTI) characterized by clinical complications including rest pain, gangrene and …

The inability of two-dimensional cell culture systems to adequately map the structure and
function of complex organs like skin necessitates the development of three-dimensional (3D) …

UVB radiation induces oxidative stress, DNA damage, and inflammation, leading to skin
wrinkling, compromised barrier function, and an increased risk of carcinogenesis …

Cutaneous chronic wounds are a major global health burden in continuous growth, because
of population aging and the higher incidence of chronic diseases, such as diabetes …

The two-dimensional nanomaterials are characterized by their ultra-thin structure, diverse
chemical functional groups, and remarkable anisotropic properties. Since its discovery in …