Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
Organometallic anti-tumor agents: targeting from biomolecules to dynamic bioprocesses
The great clinical success of cisplatin and its derivatives has convinced people that metal
complexes could play a more significant role in human cancer therapy. However, targeting …
complexes could play a more significant role in human cancer therapy. However, targeting …
Gold complexes in anticancer therapy: From new design principles to particle‐based delivery systems
G Moreno‐Alcántar, P Picchetti… - Angewandte Chemie …, 2023 - Wiley Online Library
The discovery of the medicinal properties of gold complexes has fuelled the design and
synthesis of new anticancer metallodrugs, which have received special attention due to their …
synthesis of new anticancer metallodrugs, which have received special attention due to their …
Cuproptosis: Harnessing transition metal for cancer therapy
Transition metal elements, such as copper, play diverse and pivotal roles in oncology. They
act as constituents of metalloenzymes involved in cellular metabolism, function as signaling …
act as constituents of metalloenzymes involved in cellular metabolism, function as signaling …
[HTML][HTML] Materials engineering strategies for cancer vaccine adjuvant development
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …
[HTML][HTML] Covalent organic framework nanomedicines: Biocompatibility for advanced nanocarriers and cancer theranostics applications
Nanomedicines for drug delivery and imaging-guided cancer therapy is a rapidly growing
research area. The unique properties of nanomedicines have a massive potential in solving …
research area. The unique properties of nanomedicines have a massive potential in solving …
[HTML][HTML] Activating cGAS-STING pathway with ROS-responsive nanoparticles delivering a hybrid prodrug for enhanced chemo-immunotherapy
L Cao, H Tian, M Fang, Z Xu, D Tang, J Chen, J Yin… - Biomaterials, 2022 - Elsevier
Abstract cGAS-STING pathway, as an essential intracellular immune response pathway, has
attracted much attention in tumor immunotherapy. However, low metabolic stability of …
attracted much attention in tumor immunotherapy. However, low metabolic stability of …
Poly (ethylene glycol) alternatives in biomedical applications
X Yao, C Qi, C Sun, F Huo, X Jiang - Nano Today, 2023 - Elsevier
Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …
Engineered bacteria labeled with iridium (III) photosensitizers for enhanced photodynamic immunotherapy of solid tumors
W Lin, Y Liu, J Wang, Z Zhao, K Lu, H Meng… - Angewandte …, 2023 - Wiley Online Library
Despite metal‐based photosensitizers showing great potential in photodynamic therapy for
tumor treatment, the application of the photosensitizers is intrinsically limited by their poor …
tumor treatment, the application of the photosensitizers is intrinsically limited by their poor …
Biomedical metal–organic framework materials: perspectives and challenges
A Wang, M Walden, R Ettlinger… - Advanced Functional …, 2023 - Wiley Online Library
Metal–organic framework (MOF) materials are gaining significant interest in biomedical
research, owing to their high porosity, crystallinity, and structural and compositional diversity …
research, owing to their high porosity, crystallinity, and structural and compositional diversity …