How is the olfactory map formed and interpreted in the mammalian brain?

K Mori, H Sakano - Annual review of neuroscience, 2011 - annualreviews.org
Odor signals received by odorant receptors (ORs) expressed by olfactory sensory neurons
(OSNs) in the olfactory epithelium (OE) are represented as an odor map in the olfactory bulb …

Monoallelic expression of olfactory receptors

K Monahan, S Lomvardas - Annual review of cell and …, 2015 - annualreviews.org
The sense of smell collects vital information about the environment by detecting a multitude
of chemical odorants. Breadth and sensitivity are provided by a huge number of …

[HTML][HTML] An epigenetic trap stabilizes singular olfactory receptor expression

DB Lyons, WE Allen, T Goh, L Tsai, G Barnea… - Cell, 2013 - cell.com
The molecular mechanisms regulating olfactory receptor (OR) expression in the mammalian
nose are not yet understood. Here, we identify the transient expression of histone …

Cooperative interactions enable singular olfactory receptor expression in mouse olfactory neurons

K Monahan, I Schieren, J Cheung, A Mumbey-Wafula… - Elife, 2017 - elifesciences.org
The monogenic and monoallelic expression of only one out of> 1000 mouse olfactory
receptor (ORs) genes requires the formation of large heterochromatic chromatin domains …

Neural map formation in the mouse olfactory system

H Sakano - Neuron, 2010 - cell.com
Odor signals received by odorant receptors (ORs) in the olfactory epithelium are
represented as an odor map of activated glomeruli in the olfactory bulb. In the mouse …

Maturation of the olfactory sensory neuron and its cilia

TS McClintock, N Khan, C Xie, JR Martens - Chemical Senses, 2020 - academic.oup.com
Olfactory sensory neurons (OSNs) are bipolar neurons, unusual because they turn over
continuously and have a multiciliated dendrite. The extensive changes in gene expression …

Extrasensory perception: odorant and taste receptors beyond the nose and mouth

SR Foster, E Roura, WG Thomas - Pharmacology & Therapeutics, 2014 - Elsevier
G protein-coupled receptors (GPCRs) represent the largest family of transmembrane
receptors and are prime therapeutic targets. The odorant and taste receptors account for …

[图书][B] The neurobiology of olfaction

A Menini - 2009 - taylorfrancis.com
Comprehensive Overview of Advances in OlfactionThe common belief is that human smell
perception is much reduced compared with other mammals, so that whatever abilities are …

Deletion of the core-H region in mice abolishes the expression of three proximal odorant receptor genes in cis

H Nishizumi, K Kumasaka, N Inoue… - Proceedings of the …, 2007 - National Acad Sciences
We have previously reported that a 2.1-kb homology (H) sequence, conserved between
mouse and human, regulates the odorant receptor (OR) gene MOR28 in transgenic mice …

In silico analysis of promoter region and regulatory elements of glucan endo-1, 3-beta-glucosidase encoding genes in Solanum tuberosum: cultivar DM 1-3 516 R44

A Kebede, M Kebede - Journal of Genetic Engineering and Biotechnology, 2021 - Elsevier
Abstract Background Potato (Solanum tuberosum L.) is one of the most important food crops
in the world. Pathogens remain as one of the major constraints limiting potato productivity …