Proteolipid protein (PLP) and its smaller isoform DM20 constitute the major myelin proteins
of the CNS. Mutations of the X‐linked Plp gene cause the heterogeneous syndromes of …

The two proteins, proteolipid protein and DM20, which are encoded by alternative transcripts
from the proteolipid protein (PLP) gene, are major components of central nervous system …

Pelizaeus–Merzbacher disease (PMD) is a leukodystrophy linked to the proteolipid protein
gene (PLP). We report a cellular basis for the distinction between two disease subtypes …

Pelizaeus-Merzbacher disease (PMD) is a dysmyelinating disease resulting from mutations,
deletions, or duplications of the proteolipid protein (PLP) gene. Distinguishing features of …

Mutations in the gene for proteolipid protein (PLP) have been associated with CNS
dysmyelination and abnormal oligodendrocyte death in spontaneous mouse mutants and in …

Mutations of the proteolipid protein (Plp) gene cause a generalized central nervous system
(CNS) myelin deficit in Pelizaeus‐Merzbacher disease of man and various tremor …

Differential gene expression is partially regulated by zinc finger proteins (ZFP) such as Sp1,
which may be potential targets for perturbations by environmental metals. In this paper, we …

The proteolipid protein (PLP) gene encodes two myelin-specific protein isoforms, DM-20
and PLP, which are members of the highly conserved lipophilin family of transmembrane …

Although proteolipid protein (PLP) and its DM20 isoform are the major membrane proteins of
CNS myelin, their absence causes surprisingly few developmental defects. In comparison …

The PKR-like endoplasmic reticulum kinase (PERK) pathway of the unfolded protein
response (UPR) is protective against toxic accumulations of misfolded proteins in the …