Advancing pharmacogenomics from single-gene to preemptive testing
Pharmacogenomic testing can be an effective tool to enhance medication safety and
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …
efficacy. Pharmacogenomically actionable medications are widely used, and approximately …
Implementation of pharmacogenomics: Where are we now?
S Medwid, RB Kim - British Journal of Clinical Pharmacology, 2024 - Wiley Online Library
Pharmacogenomics (PGx), examining the effect of genetic variation on interpatient variation
in drug disposition and response, has been widely studied for several decades. However, as …
in drug disposition and response, has been widely studied for several decades. However, as …
Introducing HL7 FHIR Genomics Operations: a developer-friendly approach to genomics-EHR integration
RH Dolin, BSE Heale, G Alterovitz… - Journal of the …, 2023 - academic.oup.com
Objective Enabling clinicians to formulate individualized clinical management strategies
from the sea of molecular data remains a fundamentally important but daunting task. Here …
from the sea of molecular data remains a fundamentally important but daunting task. Here …
Clinician adherence to pharmacogenomics prescribing recommendations in clinical decision support alerts
JQ Nguyen, KR Crews, BT Moore… - Journal of the …, 2023 - academic.oup.com
Thoughtful integration of interruptive clinical decision support (CDS) alerts within the
electronic health record is essential to guide clinicians on the application of …
electronic health record is essential to guide clinicians on the application of …
Pharmacogenomic clinical decision support: a scoping review
Clinical decision support (CDS) is often cited as an essential part of pharmacogenomics
(PGx) implementations. A multitude of strategies are available; however, it is unclear which …
(PGx) implementations. A multitude of strategies are available; however, it is unclear which …
The critical role of pharmacists in the clinical delivery of pharmacogenetics in the US
SB Haga - Pharmacy, 2023 - mdpi.com
Since the rebirth of pharmacogenomics (PGx) in the 1990s and 2000s, with new discoveries
of genetic variation underlying adverse drug response and new analytical technologies such …
of genetic variation underlying adverse drug response and new analytical technologies such …
Explainable artificial intelligence (XAI) in medical decision support systems (MDSS): applicability, prospects, legal implications, and challenges
The healthcare sector is very interested in machine learning (ML) and artificial intelligence
(AI). Nevertheless, applying AI applications in scientific contexts is difficult because of the …
(AI). Nevertheless, applying AI applications in scientific contexts is difficult because of the …
Impact of transitioning to an active, noninterruptive CYP2C19/proton pump inhibitor alert on prescribing patterns
A Massmann, NJ Petry - American Journal of Health-System …, 2023 - academic.oup.com
Purpose To compare rates of prescriber acceptance of interruptive and noninterruptive
clinical decision support (CDS) alerts regarding potential diminished therapeutic …
clinical decision support (CDS) alerts regarding potential diminished therapeutic …
Clinical decision support for precision dosing: opportunities for enhanced equity and inclusion in health care
Precision dosing aims to tailor doses to individual patients with the goal of improving
treatment efficacy and avoiding toxicity. Clinical decision support software (CDSS) plays a …
treatment efficacy and avoiding toxicity. Clinical decision support software (CDSS) plays a …
Understanding general practitioner and pharmacist preferences for pharmacogenetic testing in primary care: a discrete choice experiment
JH McDermott, V Sharma, GM Beaman… - The …, 2024 - nature.com
Pharmacogenetic testing in the United Kingdom's National Health Service (NHS) has
historically been reactive in nature, undertaken in the context of single gene-drug …
historically been reactive in nature, undertaken in the context of single gene-drug …