Progressive lung disease in cystic fibrosis (CF) is the life-limiting factor of this autosomal
recessive genetic disorder. Increasing implementation of CF newborn screening allows for a …

Rationale: Studies demonstrating early structural lung damage in infants and preschool
children with cystic fibrosis (CF) suggest that noninvasive monitoring will be important to …

OBJECTIVE: To assess pulmonary abnormalities detected by high-resolution computed
tomography (HRCT) in young children with cystic fibrosis (CF) and mild to moderate lung …

For effective clinical management of cystic fibrosis (CF) lung disease it is important to closely
monitor the start and progression of lung damage. The aim of this study was to investigate …

Background Cough is a prominent symptom across a range of common chronic respiratory
diseases and impacts considerably on patient health status. Methods We undertook a cross …

Background Chest X-ray, computed tomography (CT), and magnetic resonance imaging
(MRI) each have characteristic advantages and disadvantages that need to be considered in …

Rationale: The development of early lung disease in patients with cystic fibrosis (CF)
remains poorly defined. Objective: Determine whether asymptomatic infants with CF have …

The first report of computed tomography (CT) scanning to monitor cystic fibrosis (CF)–related
lung disease was published in 1986. Further publications followed, but in general there was …

The purpose of this study was to compare hyperpolarized 3 helium magnetic resonance
imaging (3 He MRI) of the lungs in adults with cystic fibrosis (CF) with high-resolution …

Purpose To develop low-dose thin-section computed tomographic (CT) protocols for
assessment of cystic fibrosis (CF) in pediatric patients and determine the clinical usefulness …