Systematic review and meta-analysis of ivermectin for treatment of COVID-19: evidence beyond the hype

MS Marcolino, KC Meira, NS Guimarães… - BMC Infectious …, 2022 - Springer
Background The role of ivermectin in the treatment of COVID-19 is still under debate, yet the
drug has been widely used in some parts of the world, as shown by impressive market data …

Mechanism of action of small-molecule agents in ongoing clinical trials for SARS-CoV-2: a review

L Zhao, S Li, W Zhong - Frontiers in Pharmacology, 2022 - frontiersin.org
Since the first reports from December 2019, COVID-19 caused an overwhelming global
pandemic that has affected 223 countries, seriously endangering public health and creating …

Efficacy of tocilizumab in the treatment of COVID‐19: An umbrella review

MM Rezaei Tolzali, M Noori, P Shokri… - Reviews in Medical …, 2022 - Wiley Online Library
Tocilizumab is an interleukin (IL)‐6 receptor inhibitor that has been proposed as a
therapeutic agent for treating coronavirus disease 2019 (COVID‐19). The aim of this …

Drug repurposing in oncology: a systematic review of randomized controlled clinical trials

I Ioakeim-Skoufa, N Tobajas-Ramos, E Menditto… - Cancers, 2023 - mdpi.com
Simple Summary Exploring the possibility of using well-known marketed drugs in new
therapeutic indications, commonly known as drug repurposing, offers certain advantages …

Efficacy and safety of baricitinib and tocilizumab in hospitalized patients with COVID-19: a comparison using systematic review and meta-analysis

JJ Cherian, M Eerike, BS Bagepally, S Das… - Frontiers in …, 2022 - frontiersin.org
Objective: This review was performed to compare the efficacy and safety among hospitalized
patients with COVID-19 who received baricitinib and those who received tocilizumab …

Meta-analyses do not establish improved mortality with ivermectin use in COVID-19

SG Rothrock, KD Weber, PA Giordano… - American journal of …, 2022 - journals.lww.com
All authors (SG Rothrock, KD Weber, M. Barneck, PA Giordano) were involved in conception
of study, design of the study, data collection and abstraction, drafting and revision of the …

A peek into Pandora's box: COVID-19 and neurodegeneration

A Chandra, A Johri - Brain Sciences, 2022 - mdpi.com
Ever since it was first reported in Wuhan, China, the coronavirus-induced disease of 2019
(COVID-19) has become an enigma of sorts with ever expanding reports of direct and …

Emerging small molecule antivirals may fit neatly into COVID-19 treatment

C Fenton, SJ Keam - Drugs & Therapy Perspectives, 2022 - Springer
Numerous treatments exist for COVID-19, the illness caused by SARS-CoV-2 virus, although
most are not well established; among these are several small molecule antiviral agents …

The clinical course and outcomes of patients hospitalized due to COVID-19 during three pandemic waves in Poland: a single center observational study

C Bieńkowski, JD Kowalska, M Paciorek… - Journal of Clinical …, 2022 - mdpi.com
Background: The first case of coronavirus disease 2019 (COVID-19) in Poland was reported
on 4 March 2020. We aim to compare the clinical course and outcomes of patients …

Green ecofriendly electrochemical sensing platform for the sensitive determination of doxycycline

AM Asran, MA Mohamed, MK Abd El-Rahman… - Heliyon, 2023 - cell.com
The detection of pharmaceutical compounds in extremely low concentrations remains a
challenge despite recent advancements in electrochemical sensing. In this study, a green …