Malaria remains a significant threat to global health, and despite concerted efforts to curb the
disease, malaria-related morbidity and mortality increased in recent years. Malaria is caused …

Humans and other mammalian species possess an endogenous circadian clock system that
has evolved in adaptation to periodically reoccurring environmental changes and drives …

Accurate diagnosis of human diseases is crucial for effective prevention, clinical treatment,
and prognosis. The World Health Organization (WHO) has provided guidelines for molecular …

Background Circadian rhythms broadly impact human health by regulating our daily
physiological and metabolic processes. The circadian clocks substantially regulate our …

Circadian rhythms are intrinsic 24-hour oscillations found in nearly all life forms. They
orchestrate key physiological and behavioral processes, allowing anticipation and response …

Abstracts Ophiocordyceps fungi manipulate ant behaviour as a transmission strategy.
Conspicuous changes in the daily timing of disease phenotypes suggest that …

ABSTRACT P-glycoprotein (P-gp) is a key component of the intestinal epithelium playing a
pivotal role in removal of toxins and efflux of endocannabinoids to prevent excessive …

Background Circadian rhythm is characterised by daily variations in biological activity to
align with the light and dark cycle. These diurnal variations, in turn, influence physiological …

The biology of disease vector arthropods is shaped by the nature of their interactions with
the hosts, which are used as their source of a blood meal, the pathogens acquired in the …

Malaria parasites exhibit a complex lifecycle, requiring extensive asexual replication in the
liver and blood of the vertebrate host, and in the haemocoel of the insect vector. Yet, they …