Love is one of our most powerful emotions, inspiring some of the greatest art, literature and
conquests of human history. Although aspects of love are surely unique to our species …

The impact of stress on brain function is increasingly recognized. Various substances are
released in response to stress and can influence distinct neuronal circuits, but the functional …

This review summarizes evidence of dysregulated reward circuitry function in a range of
neurodevelopmental and psychiatric disorders and genetic syndromes. First, the …

Stressors motivate an array of adaptive responses ranging from 'fight or flight'to an internal
urgency signal facilitating long-term goals. However, traumatic or chronic uncontrollable …

Rationale Love has long been referred to as an addiction in literature and poetry. Scientists
have often made comparisons between social attachment processes and drug addiction …

The formation of enduring relationships between adult mates (ie, pair bonds) is an integral
aspect of human social behavior and has been implicated in both physical and …

Social relationships throughout life are vital for well-being and physical and mental health. A
significant amount of research in animal models as well as in humans suggests that oxytocin …

Highlights•Social monogamy has evolved independently in distant species.•Pair bonding
has been investigated most rigorously in prairie voles.•Pair bonding is regulated by …

Oxytocin receptors in the nucleus accumbens have been implicated in the regulation of
alloparental behavior and pair bond formation in the socially monogamous prairie vole …

Humans have lived in a dynamic environment fraught with potential dangers for thousands
of years. While fear and stress were crucial for the survival of our ancestors, today, they are …