[HTML][HTML] T cell subsets and functions in atherosclerosis

R Saigusa, H Winkels, K Ley - Nature Reviews Cardiology, 2020 - nature.com
Atherosclerosis is a chronic inflammatory disease of the arterial wall and the primary
underlying cause of cardiovascular disease. Data from in vivo imaging, cell-lineage tracing …

A role for Th1-like Th17 cells in the pathogenesis of inflammatory and autoimmune disorders

AN Kamali, SM Noorbakhsh, H Hamedifar… - Molecular …, 2019 - Elsevier
Abstract The T helper 17 (Th17) cells contain a dynamic subset of CD4+ T-cells that are able
to develop into other different lineage subsets, including the Th1-like Th17 cells. These cells …

Influence of protein fold stability on immunogenicity and its implications for vaccine design

S Scheiblhofer, J Laimer, Y Machado… - Expert review of …, 2017 - Taylor & Francis
Introduction: In modern vaccinology and immunotherapy, recombinant proteins more and
more replace whole organisms to induce protective or curative immune responses …

miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity

B Li, X Wang, IY Choi, YC Wang, S Liu… - The Journal of …, 2017 - Am Soc Clin Investig
Autoreactive CD4 T cells that differentiate into pathogenic Th17 cells can trigger
autoimmune diseases. Therefore, investigating the regulatory network that modulates Th17 …

Role and potential of different T helper cell subsets in adoptive cell therapy

D Andreu-Sanz, S Kobold - Cancers, 2023 - mdpi.com
Simple Summary While most cancer immunotherapies have focused on CD8+ T cells as the
main drivers of antitumor immunity, increasing evidence indicates that CD4+ T cells also …

How pregnancy can affect autoimmune diseases progression?

MP Piccinni, L Lombardelli, F Logiodice… - Clinical and Molecular …, 2016 - Springer
Autoimmune disorders are characterized by tissue damage, caused by self-reactivity of
different effectors mechanisms of the immune system, namely antibodies and T cells. Their …

Cellular signaling pathways in medium and large vessel vasculitis

R Watanabe, GJ Berry, DH Liang, JJ Goronzy… - Frontiers in …, 2020 - frontiersin.org
Autoimmune and autoinflammatory diseases of the medium and large arteries, including the
aorta, cause life-threatening complications due to vessel wall destruction but also by wall …

Autoimmunity in common variable immunodeficiency: epidemiology, pathophysiology and management

G Azizi, H Abolhassani, MH Asgardoon… - Expert review of …, 2017 - Taylor & Francis
Introduction: Common variable immunodeficiency (CVID) comprises a large heterogeneous
group of patients with primary antibody deficiency. Areas covered: The affected patients are …

Th22 Cells Promote Osteoclast Differentiation via Production of IL-22 in Rheumatoid Arthritis

Y Miyazaki, S Nakayamada, S Kubo, K Nakano… - Frontiers in …, 2018 - frontiersin.org
T helper (Th) cells can differentiate into functionally distinct subsets and play a pivotal role in
inflammatory and autoimmune diseases such as rheumatoid arthritis (RA). Th22 cells have …

T cell subsets play an important role in the determination of the clinical outcome of Helicobacter pylori infection

A Jafarzadeh, T Larussa, M Nemati, S Jalapour - Microbial pathogenesis, 2018 - Elsevier
Helicobacter pylori (H. pylori) is one of the most prevalent human pathogen and a persistent
infection with this bacterium causes common pathologies, such as gastritis or peptic ulcers …