[HTML][HTML] Distal consequences of oral inflammation
JE Konkel, C O'Boyle, S Krishnan - Frontiers in immunology, 2019 - frontiersin.org
Periodontitis is an incredibly prevalent chronic inflammatory disease, which results in the
destruction of tooth supporting structures. However, in addition to causing tooth and alveolar …
destruction of tooth supporting structures. However, in addition to causing tooth and alveolar …
[HTML][HTML] Anti-inflammatory therapy of atherosclerosis: focusing on IKKβ
J Gan, L Guo, X Zhang, Q Yu, Q Yang, Y Zhang… - Journal of …, 2023 - Springer
Chronic low-grade inflammation has been identified as a major contributor in the
development of atherosclerosis. Nuclear Factor-κappa B (NF-κB) is a critical transcription …
development of atherosclerosis. Nuclear Factor-κappa B (NF-κB) is a critical transcription …
[HTML][HTML] Porphyromonas gingivalis lipopolysaccharides act exclusively through TLR4 with a resilience between mouse and human
Porphyromonas gingivalis is a key bacterium in chronic periodontitis, which is associated
with several chronic inflammatory diseases. Lipopolysaccharides from P. gingivalis (Pg LPS) …
with several chronic inflammatory diseases. Lipopolysaccharides from P. gingivalis (Pg LPS) …
[HTML][HTML] Human β-defensin 3 inhibits periodontitis development by suppressing inflammatory responses in macrophages
D Cui, J Lyu, H Li, L Lei, T Bian, L Li, F Yan - Molecular Immunology, 2017 - Elsevier
Abstract Human β-defensin 3 (hBD3) is a cationic peptide with immunomodulatory effects on
both innate and acquired immune responses. Periodontitis, an inflammatory disease that …
both innate and acquired immune responses. Periodontitis, an inflammatory disease that …
[HTML][HTML] Human β-defensin 3 gene modification promotes the osteogenic differentiation of human periodontal ligament cells and bone repair in periodontitis
L Li, H Jiang, R Chen, J Zhou, Y Xiao… - International Journal of …, 2020 - nature.com
Efforts to control inflammation and achieve better tissue repair in the treatment of
periodontitis have been ongoing for years. Human β-defensin 3, a broad-spectrum …
periodontitis have been ongoing for years. Human β-defensin 3, a broad-spectrum …
In-situ forming implants loaded with chlorhexidine and ibuprofen for periodontal treatment: Proof of concept study in vivo
F Batool, K Agossa, M Lizambard, C Petit… - International Journal of …, 2019 - Elsevier
Control of infection and inflammation is crucial for the success of periodontal treatment. In
this study, in-situ forming implants (ISFI) loaded with chlorhexidine dihydrochloride (CHX) …
this study, in-situ forming implants (ISFI) loaded with chlorhexidine dihydrochloride (CHX) …
Human β-defensin 3-combined gold nanoparticles for enhancement of osteogenic differentiation of human periodontal ligament cells in inflammatory …
J Zhou, Y Zhang, L Li, H Fu, W Yang… - International Journal of …, 2018 - Taylor & Francis
Objective It is a great challenge to absorb and conduct biophysicochemical interactions at
the nano-bio interface. Peptides are emerging as versatile materials whose function can be …
the nano-bio interface. Peptides are emerging as versatile materials whose function can be …
[HTML][HTML] Beta-Defensin 2 and 3 Promote Bacterial Clearance of Pseudomonas aeruginosa by Inhibiting Macrophage Autophagy through Downregulation of Early …
Y Wu, D Li, Y Wang, X Liu, Y Zhang, W Qu… - Frontiers in …, 2018 - frontiersin.org
Beta-defensins 2 and 3 (BD2 and BD3) are inducible peptides present at the sites of
infection, and they are well characterized for their antimicrobial activities and immune …
infection, and they are well characterized for their antimicrobial activities and immune …
Ligature-induced periodontitis induces systemic inflammation but does not alter acute outcome after stroke in mice
C O'Boyle, MJ Haley, E Lemarchand… - … Journal of Stroke, 2020 - journals.sagepub.com
Background Stroke is a major cause of disability and mortality. Poorer outcome after stroke
is associated with concomitant inflammatory and infectious disease. Periodontitis is a …
is associated with concomitant inflammatory and infectious disease. Periodontitis is a …
β-defensin 3 modulates macrophage activation and orientation during acute inflammatory response to Porphyromonas gingivalis lipopolysaccharide
J Lyu, T Bian, B Chen, D Cui, L Li, L Gong, F Yan - Cytokine, 2017 - Elsevier
Abstract β-defensin 3, a multifunctional antimicrobial peptide, has immuno-regulatory
activities. We investigated the modulatory mechanism of human β-defensin 3 (hBD3) on …
activities. We investigated the modulatory mechanism of human β-defensin 3 (hBD3) on …