Periodontitis is an incredibly prevalent chronic inflammatory disease, which results in the
destruction of tooth supporting structures. However, in addition to causing tooth and alveolar …

Chronic low-grade inflammation has been identified as a major contributor in the
development of atherosclerosis. Nuclear Factor-κappa B (NF-κB) is a critical transcription …

Porphyromonas gingivalis is a key bacterium in chronic periodontitis, which is associated
with several chronic inflammatory diseases. Lipopolysaccharides from P. gingivalis (Pg LPS) …

Abstract Human β-defensin 3 (hBD3) is a cationic peptide with immunomodulatory effects on
both innate and acquired immune responses. Periodontitis, an inflammatory disease that …

Efforts to control inflammation and achieve better tissue repair in the treatment of
periodontitis have been ongoing for years. Human β-defensin 3, a broad-spectrum …

Control of infection and inflammation is crucial for the success of periodontal treatment. In
this study, in-situ forming implants (ISFI) loaded with chlorhexidine dihydrochloride (CHX) …

Objective It is a great challenge to absorb and conduct biophysicochemical interactions at
the nano-bio interface. Peptides are emerging as versatile materials whose function can be …

Beta-defensins 2 and 3 (BD2 and BD3) are inducible peptides present at the sites of
infection, and they are well characterized for their antimicrobial activities and immune …

Background Stroke is a major cause of disability and mortality. Poorer outcome after stroke
is associated with concomitant inflammatory and infectious disease. Periodontitis is a …

Abstract β-defensin 3, a multifunctional antimicrobial peptide, has immuno-regulatory
activities. We investigated the modulatory mechanism of human β-defensin 3 (hBD3) on …