Nothing lasts forever: understanding microbial biodegradation of polyfluorinated compounds and perfluorinated alkyl substances
LP Wackett - Microbial biotechnology, 2022 - Wiley Online Library
Poly‐and perfluorinated chemicals, including perfluorinated alkyl substances (PFAS), are
pervasive in today's society, with a negative impact on human and ecosystem health …
pervasive in today's society, with a negative impact on human and ecosystem health …
Energy conservation in fermentations of anaerobic bacteria
W Buckel - Frontiers in Microbiology, 2021 - frontiersin.org
Anaerobic bacteria ferment carbohydrates and amino acids to obtain energy for growth. Due
to the absence of oxygen and other inorganic electron acceptors, the substrate of a …
to the absence of oxygen and other inorganic electron acceptors, the substrate of a …
Multi-Fold Computational Analysis to Discover Novel Putative Inhibitors of Isethionate Sulfite-Lyase (Isla) from Bilophila wadsworthia: Combating Colorectal Cancer …
Simple Summary Hydrogen sulfide (H2S) has been produced by certain gut bacteria and
associated with the development of inflammatory bowel disease (IBD) and colon cancer …
associated with the development of inflammatory bowel disease (IBD) and colon cancer …
Targeted vaccine development against Bilophila wadsworthia to curb colon diseases: A multiepitope approach based on reverse vaccinology and computational …
The presence of excessive hydrogen sulfide (H 2 S)-producing bacteria, particularly
Bilophila wadsworthia in appendices, is linked to a weaker colonic mucus barrier …
Bilophila wadsworthia in appendices, is linked to a weaker colonic mucus barrier …
Discovery of a New Class of Aminoacyl Radical Enzymes Expands Nature's Known Radical Chemistry
Radical enzymes, including the evolutionarily ancient glycyl radical enzyme (GRE) family,
catalyze chemically challenging reactions that are involved in a myriad of important …
catalyze chemically challenging reactions that are involved in a myriad of important …
In Vitro Reconstitution of a Bacterial Ergothioneine Sulfonate Catabolic Pathway
Q Yan, H Huang, X Zhang - ACS Catalysis, 2022 - ACS Publications
Naturally occurring l-ergothioneine is a ubiquitous histidine-derived sulfur metabolite
produced by bacteria and fungi. Plants acquire ergothioneine from their soil environment …
produced by bacteria and fungi. Plants acquire ergothioneine from their soil environment …
[HTML][HTML] Pd-catalyzed oxidative carbonylation of sulfurated substrates: Theoretical mechanistic outcomes
In the present study, a detailed computational investigation has been carried out on the
recently reported PdI 2/KI-catalyzed conversion of 1-(methylthio)-3-yn-2-ols to thiophene-3 …
recently reported PdI 2/KI-catalyzed conversion of 1-(methylthio)-3-yn-2-ols to thiophene-3 …
Rescuing activity of oxygen-damaged pyruvate formate-lyase by a spare part protein
MC Andorfer, LRF Backman, PL Li, EC Ulrich… - Journal of Biological …, 2021 - ASBMB
Pyruvate formate-lyase (PFL) is a glycyl radical enzyme (GRE) that converts pyruvate and
coenzyme A into acetyl-CoA and formate in a reaction that is crucial to the primary …
coenzyme A into acetyl-CoA and formate in a reaction that is crucial to the primary …
Structure-based identification of potential substrate antagonists for isethionate sulfite-lyase enzyme of Bilophila Wadsworthia: Towards novel therapeutic intervention …
Bilophila wadsworthia is one of the prominent sources of hydrogen sulfide (H 2 S)
production in appendices, excessive levels of which can result in a weaker colonic mucus …
production in appendices, excessive levels of which can result in a weaker colonic mucus …
Cysteine Radical and Glutamate Collaboratively Enable C–H Bond Activation and C–N Bond Cleavage in a Glycyl Radical Enzyme HplG
Hydroxyprolines are abundant in nature and widely utilized by many living organisms.
Isomerization of trans-4-hydroxy-d-proline (t4D-HP) to generate 2-amino-4-ketopentanoate …
Isomerization of trans-4-hydroxy-d-proline (t4D-HP) to generate 2-amino-4-ketopentanoate …