Exposure to per-and polyfluoroalkyl substances and markers of liver injury: a systematic review and meta-analysis

E Costello, S Rock, N Stratakis, SP Eckel… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Experimental evidence indicates that exposure to certain pollutants is
associated with liver damage. Per-and polyfluoroalkyl substances (PFAS) are persistent …

Nonalcoholic fatty liver disease: a challenge from mechanisms to therapy

G Tarantino, V Citro, D Capone - Journal of clinical medicine, 2019 - mdpi.com
Focusing on previously published mechanisms of non-alcoholic fatty liver disease (NAFLD),
their uncertainty does not always permit a clear elucidation of the grassroot alterations that …

[HTML][HTML] Association of per-and polyfluoroalkyl substance exposure with fatty liver disease risk in US adults

X Zhang, L Zhao, A Ducatman, C Deng… - JHEP Reports, 2023 - Elsevier
Background & Aims Per-and polyfluoroalkyl substances (PFAS) are widespread pollutants
with demonstrated hepatotoxicity. Few studies have examined the association between …

Crosstalk between plasma cytokines, inflammation, and liver damage as a new strategy to monitoring NAFLD progression

TCM Fontes-Cal, RT Mattos, NI Medeiros… - Frontiers in …, 2021 - frontiersin.org
Cytokines are involved in the immunopathogenesis of nonalcoholic fatty liver disease
(NAFLD), but the relationship between them and clinical parameters of NAFLD progression …

Oxidative stress and pro-inflammatory status in patients with non-alcoholic fatty liver disease

M Monserrat-Mesquida, M Quetglas-Llabrés, M Abbate… - Antioxidants, 2020 - mdpi.com
Background: Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive fat
accumulation, especially triglycerides, in hepatocytes. If the pathology is not properly …

Heme-oxygenase and lipid mediators in obesity and associated cardiometabolic diseases: Therapeutic implications

JA McClung, L Levy, V Garcia, DE Stec… - Pharmacology & …, 2022 - Elsevier
Obesity-mediated metabolic syndrome remains the leading cause of death worldwide.
Among many potential targets for pharmacological intervention, a promising strategy …

Therapeutic application and construction of bilirubin incorporated nanoparticles

Q Yao, R Chen, V Ganapathy, L Kou - Journal of Controlled Release, 2020 - Elsevier
Bilirubin is a yellow-colored metabolite of heme degradation (a bile pigment), once believed
to be toxic, but recently recognized as a powerful endogenous antioxidant of physiologic …

Effect of COVID-19 pandemic on patients who have undergone liver transplantation: retrospective cohort study

S Akbulut, FH Yagin, TT Sahin, IU Garzali… - Journal of clinical …, 2023 - mdpi.com
Background: In liver transplant (LT) recipients, immunosuppressive therapy may potentially
increase the risk of severe COVID-19 and may increase the mortality in patients. However …

Dietary fiber intake and non-alcoholic fatty liver disease: The mediating role of obesity

Y Zhu, H Yang, Y Zhang, S Rao, Y Mo… - Frontiers in Public …, 2023 - frontiersin.org
Background and aims Dietary pattern rich in fiber is negatively associated with the risk of
non-alcoholic fatty liver disease (NAFLD). Meanwhile, obesity is a known predisposing …

Nanodrug delivery systems for metabolic chronic liver diseases: advances and perspectives

F Athanasopoulou, M Manolakakis, S Vernia… - …, 2023 - Taylor & Francis
Nanomedicines are revolutionizing healthcare as recently demonstrated by the
Pfizer/BioNTech and Moderna COVID-2019 vaccines, with billions of doses administered …