Ultra-sensitive electrochemical aptasensor for label-free detection of Aflatoxin B1 in wheat flour sample using factorial design experiments

F Rahimi, H Roshanfekr, H Peyman - Food Chemistry, 2021 - Elsevier
Considering the significance of mycotoxin detection in food industries, herein, an
ultrasensitive aptasensor was developed based on aflatoxin B1 aptamer immobilized on …

Polyhydroxyalkanoate (PHA) biosynthesis from directly valorized ragi husk and sesame oil cake by Bacillus megaterium strain Ti3: Statistical optimization and …

N Israni, S Shivakumar - International journal of biological macromolecules, 2020 - Elsevier
Polyhydroxyalkanoates (PHAs) signify the most promising biological substitute to
petrochemical plastics. Renewable and inexpensive agro-industrial by-products can be …

Analytical 'Quality-by-Design'paradigm in development of a RP-HPLC method for the estimation of cilnidipine in nanoformulations: Forced degradation studies and …

SM Marques, RK Shirodkar, L Kumar - Microchemical Journal, 2023 - Elsevier
The present study focuses on optimizing, developing, and validating a sensitive and specific
reversed-phase high-performance liquid chromatography (RP-HPLC) method for the …

Optimization of ultrasonic‐assisted extraction conditions for bioactive components from coffee leaves using the Taguchi design and response surface methodology

X Chen, J Ding, D Ji, S He, H Ma - Journal of food science, 2020 - Wiley Online Library
Coffee leaves contain various bioactive compounds that are beneficial for human health.
However, there are very limited researches related to the extraction of the bioactive …

Pretreatment and optimization of reducing sugar extraction from indigenous microalgae grown on brewery wastewater for bioethanol production

Z Yirgu, S Leta, A Hussen, MM Khan - Biomass Conversion and …, 2023 - Springer
The aim of this study was to select a suitable pretreatment method and optimize total
reducing sugar extraction from indigenous Scenedesmus sp. grown on brewery wastewater …

Quality by design‐steered development and validation of analytical and bioanalytical methods for raloxifene: Application of Monte Carlo simulations and variance …

A Pant, G Sharma, S Saini, A Jain… - Biomedical …, 2023 - Wiley Online Library
A sensitive, rapid, reproducible, and economical HPLC method is reported for the
quantification of raloxifene hydrochloride employing Quality by Design (QbD) principles …

Evaluation of energy consumption pattern in rice processing using Taguchi and artificial neural network approaches

MS Sanusi, R Akinoso - Agricultural Engineering International: CIGR …, 2022 - cigrjournal.org
This study was designed to evaluate and model the impacts of processing parameters
(steaming time, soaking time, paddy moisture content and soaking temperature) on the …

The development and optimisation of an HPLC‐based in vitro serum stability assay for a calcitonin gene‐related peptide receptor antagonist peptide

V D'Aloisio, A Schofield, DA Kendall… - Journal of Peptide …, 2024 - Wiley Online Library
Evaluation of the stability of peptide drug candidates in biological fluids, such as blood
serum, is of high importance during the lead optimisation phase. Here, we describe the …

Development and validation of a stability-indicating RP-HPLC method of cholecalciferol in bulk and pharmaceutical formulations: Analytical quality by design …

D Suryawanshi, DK Jha, U Shinde… - Journal of Applied …, 2019 - japsonline.com
The present article utilized analytical quality by design (AQbD) methodology to optimize
chromatographic conditions for the routine analysis of Cholecalciferol (CHL). Taguchi …

Use of real-time cellular analysis and Plackett-Burman design to develop the serum-free media for PC-3 prostate cancer cells

A Zhao, F Chen, C Ning, H Wu, H Song, Y Wu… - PLoS …, 2017 - journals.plos.org
In this study, we developed a rapid strategy to screen a serum-free medium for culturing the
anchorage-dependent PC-3 prostate cancer cells, which was going to be prepared in large …