Aspirin and antiplatelet treatments in cancer
DL Tao, S Tassi Yunga, CD Williams… - Blood, The Journal of …, 2021 - ashpublications.org
Platelets have been hypothesized to promote certain neoplastic malignancies; however,
antiplatelet drugs are still not part of routine pharmacological cancer prevention and …
antiplatelet drugs are still not part of routine pharmacological cancer prevention and …
Multifaceted functions of platelets in cancer: from tumorigenesis to liquid biopsy tool and drug delivery system
Platelets contribute to several types of cancer through plenty of mechanisms. Upon
activation, platelets release many molecules, including growth and angiogenic factors …
activation, platelets release many molecules, including growth and angiogenic factors …
Classification of red cell dynamics with convolutional and recurrent neural networks: a sickle cell disease case study
The fraction of red blood cells adopting a specific motion under low shear flow is a promising
inexpensive marker for monitoring the clinical status of patients with sickle cell disease. Its …
inexpensive marker for monitoring the clinical status of patients with sickle cell disease. Its …
Whole blood viscosity and red blood cell adhesion: Potential biomarkers for targeted and curative therapies in sickle cell disease
Sickle cell disease (SCD) is a recessive genetic blood disorder exhibiting abnormal blood
rheology. Polymerization of sickle hemoglobin, due to a point mutation in the β‐globin gene …
rheology. Polymerization of sickle hemoglobin, due to a point mutation in the β‐globin gene …
Microfluidic assessment of red blood cell mediated microvascular occlusion
Abnormal red blood cell (RBC) deformability contributes to hemolysis, thrombophilia,
inflammation, and microvascular occlusion in various circulatory diseases. A quantitative …
inflammation, and microvascular occlusion in various circulatory diseases. A quantitative …
Microfluidic electrical impedance assessment of red blood cell-mediated microvascular occlusion
Alterations in the deformability of red blood cells (RBCs), occurring in hemolytic blood
disorders such as sickle cell disease (SCD), contribute to vaso-occlusion and disease …
disorders such as sickle cell disease (SCD), contribute to vaso-occlusion and disease …
Size and density measurements of single sickle red blood cells using microfluidic magnetic levitation
Single cells have unique biophysical signatures that can rapidly change during various
disease states. For instance, cellular density is an inherent property differing between cell …
disease states. For instance, cellular density is an inherent property differing between cell …
Motion blur microscopy: in vitro imaging of cell adhesion dynamics in whole blood flow
U Goreke, A Gonzales, B Shipley, M Tincher… - Nature …, 2024 - nature.com
Imaging and characterizing the dynamics of cellular adhesion in blood samples is of
fundamental importance in understanding biological function. In vitro microscopy methods …
fundamental importance in understanding biological function. In vitro microscopy methods …
The evolving treatment landscape for children with sickle cell disease
Sickle cell disease is the most common inherited pathological haemoglobinopathy. Over the
past 30 years, disease-related morbidity and mortality have improved in high-income …
past 30 years, disease-related morbidity and mortality have improved in high-income …
Antiplatelet therapy for patients with COVID-19: Systematic review and meta-analysis of observational studies and randomized controlled trials
X Zong, X Wang, Y Liu, Z Li, W Wang, D Wei… - Frontiers in …, 2022 - frontiersin.org
Background Hyperinflammation and coagulopathy are hallmarks of COVID-19 and
synergistically contribute to illness progression. Antiplatelet agents have been proposed as …
synergistically contribute to illness progression. Antiplatelet agents have been proposed as …