Quantum mechanical studies on the photophysics and the photochemistry of nucleic acids and nucleobases
The photophysics and photochemistry of DNA is of great importance due to the potential
damage of the genetic code by UV light. Quantum mechanical studies have played a key …
damage of the genetic code by UV light. Quantum mechanical studies have played a key …
Life in the light: nucleic acid photoproperties as a legacy of chemical evolution
AA Beckstead, Y Zhang, MS de Vries… - Physical Chemistry …, 2016 - pubs.rsc.org
Photophysical investigations of the canonical nucleobases that make up DNA and RNA
during the past 15 years have revealed that excited states formed by the absorption of UV …
during the past 15 years have revealed that excited states formed by the absorption of UV …
Physical non-equilibria for prebiotic nucleic acid chemistry
A Ianeselli, A Salditt, C Mast, B Ercolano… - Nature Reviews …, 2023 - nature.com
The prebiotic replication of DNA and RNA is a complex interplay between chemistry and the
environment. Factors that have direct and indirect effects on prebiotic chemistry include …
environment. Factors that have direct and indirect effects on prebiotic chemistry include …
Early events of DNA photodamage
WJ Schreier, P Gilch, W Zinth - Annual review of physical …, 2015 - annualreviews.org
Ultraviolet (UV) radiation is a leading external hazard to the integrity of DNA. Exposure to UV
radiation triggers a cascade of chemical reactions, and many molecular products …
radiation triggers a cascade of chemical reactions, and many molecular products …
Triplet Excimer Formation in a DNA Duplex with Silver Ion-Mediated Base Pairs
L Martínez-Fernández, FR Kohl, Y Zhang… - Journal of the …, 2024 - ACS Publications
The dynamics of excited electronic states in self-assembled structures formed between silver
(I) ions and cytosine-containing DNA strands or monomeric cytosine derivatives were …
(I) ions and cytosine-containing DNA strands or monomeric cytosine derivatives were …
UV-induced charge transfer states in DNA promote sequence selective self-repair
Absorption of UV-radiation in nucleotides initiates a number of photophysical and
photochemical processes, which may finally cause DNA damage. One major decay channel …
photochemical processes, which may finally cause DNA damage. One major decay channel …
Multiple electronic and structural factors control cyclobutane pyrimidine dimer and 6–4 thymine–thymine photodimerization in a DNA duplex
I Conti, L Martínez‐Fernández… - … A European Journal, 2017 - Wiley Online Library
The T–T photodimerization paths leading to the formation of cyclobutane pyrimidine dimer
(CPD) and 6–4 pyrimidine pyrimidone (64‐PP), the two main DNA photolesions, have been …
(CPD) and 6–4 pyrimidine pyrimidone (64‐PP), the two main DNA photolesions, have been …
Sequence dependent UV damage of complete pools of oligonucleotides
CL Kufner, S Krebs, M Fischaleck… - Scientific Reports, 2023 - nature.com
Understanding the sequence-dependent DNA damage formation requires probing a
complete pool of sequences over a wide dose range of the damage-causing exposure. We …
complete pool of sequences over a wide dose range of the damage-causing exposure. We …
Excited-state dynamics of DNA duplexes with different H-bonding motifs
Y Zhang, K de La Harpe, AA Beckstead… - The Journal of …, 2016 - ACS Publications
The excited-state dynamics of three distinct forms of the d (GC) 9· d (GC) 9 DNA duplex were
studied by combined time-resolved infrared experiments and quantum mechanical …
studied by combined time-resolved infrared experiments and quantum mechanical …
The photophysics of nucleic acids: Consequences for the emergence of life
Absorption of ultraviolet (UV) radiation can trigger a variety of photophysical and
photochemical reactions in nucleic acids. In the prebiotic era, on the surface of the early …
photochemical reactions in nucleic acids. In the prebiotic era, on the surface of the early …