[HTML][HTML] Lipopolysaccharide-induced model of neuroinflammation: mechanisms of action, research application and future directions for its use

A Skrzypczak-Wiercioch, K Sałat - Molecules, 2022 - mdpi.com
Despite advances in antimicrobial and anti-inflammatory therapies, inflammation and its
consequences still remain a significant problem in medicine. Acute inflammatory responses …

Apoptosis in Alzheimer's disease: insight into the signaling pathways and therapeutic avenues

S Kumari, R Dhapola, DHK Reddy - Apoptosis, 2023 - Springer
Alzheimer's disease (AD) is characterized by the accumulation of hyperphosphorylated tau
and amyloid-β (Aβ) protein resulting in synaptic loss and apoptosis. Aβ and tau deposition …

[HTML][HTML] Neuroinflammation in vascular cognitive impairment and dementia: current evidence, advances, and prospects

Z Tian, X Ji, J Liu - International Journal of Molecular Sciences, 2022 - mdpi.com
Vascular cognitive impairment and dementia (VCID) is a major heterogeneous brain
disease caused by multiple factors, and it is the second most common type of dementia in …

[HTML][HTML] Role of Microglia and Astrocytes in Alzheimer's Disease: From Neuroinflammation to Ca2+ Homeostasis Dysregulation

G Di Benedetto, C Burgaletto, CM Bellanca, A Munafò… - Cells, 2022 - mdpi.com
Alzheimer's disease (AD) is the most common form of dementia worldwide, with a complex,
poorly understood pathogenesis. Cerebral atrophy, amyloid-β (Aβ) plaques, and …

[HTML][HTML] Gut liver brain axis in diseases: the implications for therapeutic interventions

M Yan, S Man, B Sun, L Ma, L Guo, L Huang… - Signal Transduction and …, 2023 - nature.com
Gut-liver-brain axis is a three-way highway of information interaction system among the
gastrointestinal tract, liver, and nervous systems. In the past few decades, breakthrough …

[HTML][HTML] Inflammatory processes in alzheimer's disease—pathomechanism, diagnosis and treatment: a review

B Twarowski, M Herbet - International journal of molecular sciences, 2023 - mdpi.com
Alzheimer's disease is one of the most commonly diagnosed cases of senile dementia in the
world. It is an incurable process, most often leading to death. This disease is multifactorial …

[HTML][HTML] New insights into the role and mechanisms of ginsenoside Rg1 in the management of Alzheimer's disease

J Wu, Y Yang, Y Wan, J Xia, JF Xu, L Zhang… - Biomedicine & …, 2022 - Elsevier
Alzheimer's disease (AD) is a common neurodegenerative disorder in the elderly
characterized by memory loss and cognitive dysfunction. The pathogenesis of AD is …

[HTML][HTML] Immunopharmacological activities of luteolin in chronic diseases

L Huang, MY Kim, JY Cho - International Journal of Molecular Sciences, 2023 - mdpi.com
Flavonoids have been shown to have anti-oxidative effects, as well as other health benefits
(eg, anti-inflammatory and anti-tumor functions). Luteolin (3′, 4′, 5, 7-tetrahydroxyflavone) …

[HTML][HTML] Mechanisms of ferroptosis in Alzheimer's disease and therapeutic effects of natural plant products: a review

D Zhao, K Yang, H Guo, J Zeng, S Wang, H Xu… - Biomedicine & …, 2023 - Elsevier
Neurodegenerative diseases, such as Alzheimer's disease (AD), are characterized by
massive loss of specific neurons. It is a progressive disabling, severe and fatal complex …

[HTML][HTML] Is hormone replacement therapy a risk factor or a therapeutic option for Alzheimer's disease?

ZB Mills, RLM Faull, A Kwakowsky - International Journal of Molecular …, 2023 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for
more than half of all dementia cases in the elderly. Interestingly, the clinical manifestations of …