Autoimmune hepatitis (AIH) is a chronic autoimmune liver disease that can lead to
hepatocyte destruction, inflammation, liver fibrosis, cirrhosis, and liver failure. The diagnosis …

Peripheral helper T cells (Tph) are a specialized subset of CD4+ T cells with the ability to
help B cells and induce antibody production. Although usually located in ectopic lymphoid …

Despite advances in understanding systemic lupus erythematosus (SLE), many challenges
remain in unraveling the precise mechanisms behind the disease's development and …

The success of checkpoint inhibitors (CPIs) for cancer has been tempered by immune-
related adverse effects including colitis. CPI-induced colitis is hallmarked by expansion of …

Background Primary membranous nephropathy (PMN) is usually caused by anti-
phospholipase A2 receptor (PLA2R) autoantibodies. There are different therapeutic options …

Despite major progress in the treatment of autoimmune diseases in the past two decades,
most therapies do not cure disease and can be associated with increased risk of infection …

A new population of peripheral helper T (Tph) cells has been identified and contributed to
various autoimmune diseases. Tph cells can secrete interleukin-21 (IL-21), interferon (IFN) …

Relapse after immunosuppression (IS) treatment withdrawal is frequent in patients with
Autoimmune Hepatitis (AIH), and non-invasive biomarkers predictive of this risk are lacking …

Aim and background Tertiary lymphoid structures (TLS) are increasingly recognized for their
role in immunity. Despite growing interest, a systematic bibliometric analysis of TLS-related …

Background Klebsiella pneumoniae is a common Gram-negative bacterium. Blood infection
caused by K. pneumoniae is one of the most common causes of human sepsis, which …