MicroRNAs expression in ox-LDL treated HUVECs: MiR-365 modulates apoptosis and Bcl-2 expression
B Qin, B Xiao, D Liang, J Xia, Y Li, H Yang - Biochemical and biophysical …, 2011 - Elsevier
Endothelial cells (ECs) apoptosis induced by oxidized low-density lipoprotein (ox-LDL) is
thought to play a critical role in atherosclerosis. MicroRNAs (miRNAs) are a class of …
thought to play a critical role in atherosclerosis. MicroRNAs (miRNAs) are a class of …
[HTML][HTML] Calcium signals between the ryanodine receptor-and mitochondria critically regulate the effects of arsenite on mitochondrial superoxide formation and on the …
A low concentration of arsenite (6 h), selectively stimulating the intraluminal crosstalk
between the inositol-1, 4, 5-triphosphate receptor and the ryanodine receptor (RyR) …
between the inositol-1, 4, 5-triphosphate receptor and the ryanodine receptor (RyR) …
Melatonin attenuates arsenite‐induced apoptosis in rat brain: involvement of mitochondrial and endoplasmic reticulum pathways and aggregation of α‐synuclein
AMY Lin, SF Fang, PL Chao… - Journal of pineal …, 2007 - Wiley Online Library
In the present study, the protective effect of melatonin on sodium arsenite (arsenite)‐induced
apoptosis was investigated. Local infusion of arsenite elevated lipid peroxidation and …
apoptosis was investigated. Local infusion of arsenite elevated lipid peroxidation and …
[HTML][HTML] Overexpression of Bcl-2 in vascular endothelium inhibits the microvascular lesions of diabetic retinopathy
TS Kern, Y Du, CM Miller, DA Hatala… - The American journal of …, 2010 - Elsevier
Recent studies on the pathogenesis of diabetic retinopathy have focused on correcting
adverse biochemical alterations, but there have been fewer efforts to enhance prosurvival …
adverse biochemical alterations, but there have been fewer efforts to enhance prosurvival …
Endoplasmic reticulum stress is involved in arsenite-induced oxidative injury in rat brain
AMY Lin, PL Chao, SF Fang, CW Chi… - Toxicology and applied …, 2007 - Elsevier
The mechanism underlying sodium arsenite (arsenite)-induced neurotoxicity was
investigated in rat brain. Arsenite was locally infused in the substantia nigra (SN) of …
investigated in rat brain. Arsenite was locally infused in the substantia nigra (SN) of …
Functional organization of the endoplasmic reticulum dictates the susceptibility of target cells to arsenite-induced mitochondrial superoxide formation, mitochondrial …
A Guidarelli, A Catalani, A Spina, E Varone… - Food and Chemical …, 2021 - Elsevier
Arsenite induces many critical effects associated with the formation of reactive oxygen
species (ROS) through different mechanisms. We focused on Ca 2+-dependent …
species (ROS) through different mechanisms. We focused on Ca 2+-dependent …
The fast-halo assay for the detection of DNA damage
The need for express screening of the DNA damaging potential of chemicals has
progressively increased over the past 20 years due to the wide number of new synthetic …
progressively increased over the past 20 years due to the wide number of new synthetic …
Inhibition of complex III promotes loss of Ca2+ dependence for mitochondrial superoxide formation and permeability transition evoked by peroxynitrite
In intact U937 cells, peroxynitrite promotes the mitochondrial formation of superoxide via a
Ca2+-dependent mechanism involving inhibition of complex III. Superoxide then readily …
Ca2+-dependent mechanism involving inhibition of complex III. Superoxide then readily …
The dual role of mitochondrial superoxide in arsenite toxicity: signaling at the boundary between apoptotic commitment and cytoprotection
Arsenite toxicity is in numerous cellular systems dependent on the formation of reactive
oxygen and or nitrogen species. This is also true in U937 cells in which the metalloid …
oxygen and or nitrogen species. This is also true in U937 cells in which the metalloid …
Inhibition of activity/expression, or genetic deletion, of ERO1α blunts arsenite geno-and cyto-toxicity
Our recent studies suggest that arsenite stimulates the crosstalk between the inositol 1, 4, 5-
triphosphate receptor (IP 3 R) and the ryanodine receptor (RyR) via a mechanism …
triphosphate receptor (IP 3 R) and the ryanodine receptor (RyR) via a mechanism …