The heme peroxidase family generates a battery of oxidants both for synthetic purposes, and
in the innate immune defence against pathogens. Myeloperoxidase (MPO) is the most …

The volume of publications on the role of reactive oxygen species (ROS) in biological
processes has been increasing exponentially over the last decades. ROS in large amounts …

During an inflammatory response in the gut, some commensal bacteria such as E. coli can
thrive and contribute to disease. Here we demonstrate that enterobactin (Ent), a catecholate …

Background Potential routes whereby systemic inflammation, oxidative stress and
mitochondrial dysfunction may drive the development of endothelial dysfunction and …

Ceruloplasmin (CP) is a mammalian blood plasma ferroxidase. More than 95% of the
copper found in plasma is carried by this protein, which is a member of the multicopper …

Inflammation and its resolution are the result of the balance between pro-inflammatory and
pro-resolving factors, such as specialized pro-resolving mediators (SPMs). This balance is …

Copper-containing plasma protein ceruloplasmin (Cp) forms a complex with lactoferrin (Lf),
an iron-binding protein, and with the heme-containing myeloperoxidase (Mpo). In case of …

Low-density lipoprotein (LDL) modified by hypochlorous acid (HOCl) produced by
myeloperoxidase (MPO) is present in atherosclerotic lesions, where it is implicated in the …

The function of oxidatively modified low-density lipoprotein (oxLDL) in the progression of
cardiovascular diseases has been extensively investigated and well-characterized with …

LDL plays an important role in atherosclerotic plaque formation and macrophage
differentiation. However, there is no report regarding the oxidation degree of LDL and …