Telomeres are specialized nucleoprotein structures at the ends of linear chromosomes that
prevent the activation of DNA damage response and repair pathways. Numerous factors …

The late 1990s were banner years in molecular neuroscience; seminal studies
demonstrated that local protein synthesis, at or near synapses, was necessary for synaptic …

The infusion of coronavirus disease 2019 (COVID-19) patients with mesenchymal stem cells
(MSCs) potentially improves clinical symptoms, but the underlying mechanism remains …

Memory B cells (MBCs) can persist for a lifetime, but the mechanisms that allow their long-
term survival remain poorly understood. Here, we isolated and analyzed human splenic …

Telomeres are non-coding DNA sequences that protect chromosome ends and shorten with
age. Short telomere length (TL) is associated with chronic diseases and …

Abstract Described by Guido Fanconi almost 100 years ago, Fanconi anemia (FA) is a rare
genetic disease characterized by developmental abnormalities, bone marrow failure (BMF) …

Glioblastoma is the most common type of malignant primary brain tumor and displays highly
aggressive and heterogeneous phenotypes. The transcription factor STAT3 has been …

Telomeres are nucleoprotein structures at the end of chromosomes. The telomerase
complex, constituted of the catalytic subunit TERT, the RNA matrix h TR and several …

Learning objectives Inherited bone marrow failure syndromes (IBMFSs) are a group of
disorders typified by impaired production of 1 or several blood cell types. The telomere …

In germ cells, small non‐coding PIWI‐interacting RNAs (piRNAs) work to silence harmful
transposons to maintain genomic stability and regulate gene expression to ensure fertility …